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- W2227967874 abstract "Ozet: Vulva skuamoz hucreli karsinomu tanisiyla radyoterapi uygulanan hastalarda tedavi sonuclari ve rekurrens ozelliklerinin degerlendirilmesi. Agustos 2006-Agustos 2014 arasinda radyoterapi uygulanan vulva skuamoz hucreli karsinomu tanili 12 kadin hasta, tumor ve tedavi ozelliklerine gore retrospektif olarak degerlendirilmistir. 3 (%25) hastaya radikal, 9’una (%75) adjuvan medyan 50.4 (30-63) Gy RT uygulanmis, 4 (%33) hastaya eszamanli kemoterapi verilmistir. Medyan yas 65 (59-90); medyan izlem 16 (4-65) aydir. Medyan genel, hastaliksiz ve uzak metastazsiz sagkalim sirasiyla 16 (4-65), 14 (0-65) ve 16 (4-65) aydir. Hastalarin 7’si (%58) hastaliksiz izlemde olup diger 5 (%42) hastada 1 (%8.3) yerel, 2 (%17) bolgesel, 1 (%8.3) yerel-bolgesel nuks ve 1 (%8.3) yerel-bolgesel-uzak hastalik saptanmistir. Nuks sonrasi eksitus olan 3 hastada da inguinal nuks mevcuttur. Vulva skuamoz hucreli karsinomunda sagkalim ve hastalik kontrolunu etkileyen en onemli faktor lenf nodu metastazi olup calismamizda nuks gelisen 5 hastadan 4’unde inguinal lenf nodu metastazi saptanmistir. ANAHTAR SOZCUKLER: vulva kanseri, radyoterapi, prognostik faktorler RECURRENCE PATERNS OF VULVAR SQUAMOUS CELL CARCINOMA FOLLOWED BY RADIOTHERAPY Abstract: Evaluation of treatment outcomes and recurrence paterns of the patients diagnosis with vulvar squamous cell carcinoma treated with radiotherapy. The patients diagnosed by vulvar squamous cell carcinoma between August 2006 and August 2014 were retrospectively evaluated according to tumor and treatment characteristics. Adjuvant radiotherapy was applied three of the twelve patients (25%) and radical radiotherapy was applied the other 9 patients (75%).The median radiotherapy dose was 50.4 (30-63) Gy. Concurrent chemotherapy is given to 4 patients (33%). Median age was 65 (range 59 to 90); median follow-up time was 16 (range 4 to 65) months. The overall survival, relapse-free survival and distant metastasis-free survival were 16 (4-65), 14 (0-65) and 16 (4-65) months respectively. Seven (58%) patients were disease free. One (8.3%) local, 2 (17%) regional, 1 (8.3%) local-regional recurrence and 1 (8.3%) local- regional recurrence with distant metastasis were observed. Three patients who had recurrence died with inguinal recurrence. Lymph node metastasis is the most important factor affecting survival and disease control in vulvar squamous cell carcinoma. In our study, four of five patients who developed recurrence had inguinal lymph node metastasis. KEYWORDS: vulvar cancer, radiotherapy, prognostic factors" @default.
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- W2227967874 date "2016-01-19" @default.
- W2227967874 modified "2023-09-27" @default.
- W2227967874 title "VULVA SKUAMÖZ HÜCRELİ KARSİNOMUNDA RADYOTERAPİ SONRASI REKÜRRENS ÖZELLİKLERİ / RECURRENCE PATERNS OF VULVAR SQUAMOUS CELL CARCINOMA FOLLOWED BY RADIOTHERAPY" @default.
- W2227967874 doi "https://doi.org/10.20515/otd.91977" @default.
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