FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2227983549> ?p ?o ?g. }

• W2227983549 endingPage "e0146384" @default.
• W2227983549 startingPage "e0146384" @default.
• W2227983549 abstract "We present a completely revised generation of a modular micro-NMR detector, featuring an active sample volume of ∼ 100 nL, and an improvement of 87% in probe efficiency. The detector is capable of rapidly screening different samples using exchangeable, application-specific, MEMS-fabricated, microfluidic sample containers. In contrast to our previous design, the sample holder chips can be simply sealed with adhesive tape, with excellent adhesion due to the smooth surfaces surrounding the fluidic ports, and so withstand pressures of ∼2.5 bar, while simultaneously enabling high spectral resolution up to 0.62 Hz for H2O, due to its optimised geometry. We have additionally reworked the coil design and fabrication processes, replacing liquid photoresists by dry film stock, whose final thickness does not depend on accurate volume dispensing or precise levelling during curing. We further introduced mechanical alignment structures to avoid time-intensive optical alignment of the chip stacks during assembly, while we exchanged the laser-cut, PMMA spacers by diced glass spacers, which are not susceptible to melting during cutting. Doing so led to an overall simplification of the entire fabrication chain, while simultaneously increasing the yield, due to an improved uniformity of thickness of the individual layers, and in addition, due to more accurate vertical positioning of the wirebonded coils, now delimited by a post base plateau. We demonstrate the capability of the design by acquiring a 1H spectrum of ∼ 11 nmol sucrose dissolved in D2O, where we achieved a linewidth of 1.25 Hz for the TSP reference peak. Chemical shift imaging experiments were further recorded from voxel volumes of only ∼ 1.5nL, which corresponded to amounts of just 1.5 nmol per voxel for a 1 M concentration. To extend the micro-detector to other nuclei of interest, we have implemented a trap circuit, enabling heteronuclear spectroscopy, demonstrated by two 1H/13C 2D HSQC experiments." @default.
• W2227983549 created "2016-06-24" @default.
• W2227983549 creator A5008731037 @default.
• W2227983549 creator A5010760941 @default.
• W2227983549 creator A5025797489 @default.
• W2227983549 creator A5035092090 @default.
• W2227983549 creator A5042137175 @default.
• W2227983549 creator A5047998886 @default.
• W2227983549 creator A5072076684 @default.
• W2227983549 creator A5089713199 @default.
• W2227983549 date "2016-01-05" @default.
• W2227983549 modified "2023-09-30" @default.
• W2227983549 title "Heteronuclear Micro-Helmholtz Coil Facilitates µm-Range Spatial and Sub-Hz Spectral Resolution NMR of nL-Volume Samples on Customisable Microfluidic Chips" @default.
• W2227983549 cites W1967666166 @default.
• W2227983549 cites W1975108181 @default.
• W2227983549 cites W1976013989 @default.
• W2227983549 cites W1986400591 @default.
• W2227983549 cites W1999892194 @default.
• W2227983549 cites W2005993564 @default.
• W2227983549 cites W2011320038 @default.
• W2227983549 cites W2011435619 @default.
• W2227983549 cites W2018018298 @default.
• W2227983549 cites W2019427433 @default.
• W2227983549 cites W2031914974 @default.
• W2227983549 cites W2034223990 @default.
• W2227983549 cites W2036021992 @default.
• W2227983549 cites W2039235747 @default.
• W2227983549 cites W2049697770 @default.
• W2227983549 cites W2076194502 @default.
• W2227983549 cites W2076216336 @default.
• W2227983549 cites W2086742151 @default.
• W2227983549 cites W2089877540 @default.
• W2227983549 cites W2099202702 @default.
• W2227983549 cites W2135545364 @default.
• W2227983549 cites W2148366851 @default.
• W2227983549 cites W2152379769 @default.
• W2227983549 cites W2154108863 @default.
• W2227983549 cites W2169120093 @default.
• W2227983549 cites W4229743141 @default.
• W2227983549 cites W4230713808 @default.
• W2227983549 cites W2085578006 @default.
• W2227983549 doi "https://doi.org/10.1371/journal.pone.0146384" @default.
• W2227983549 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4701473" @default.
• W2227983549 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26730968" @default.
• W2227983549 hasPublicationYear "2016" @default.
• W2227983549 type Work @default.
• W2227983549 sameAs 2227983549 @default.
• W2227983549 citedByCount "46" @default.
• W2227983549 countsByYear W22279835492016 @default.
• W2227983549 countsByYear W22279835492017 @default.
• W2227983549 countsByYear W22279835492018 @default.
• W2227983549 countsByYear W22279835492019 @default.
• W2227983549 countsByYear W22279835492020 @default.
• W2227983549 countsByYear W22279835492021 @default.
• W2227983549 countsByYear W22279835492022 @default.
• W2227983549 countsByYear W22279835492023 @default.
• W2227983549 crossrefType "journal-article" @default.
• W2227983549 hasAuthorship W2227983549A5008731037 @default.
• W2227983549 hasAuthorship W2227983549A5010760941 @default.
• W2227983549 hasAuthorship W2227983549A5025797489 @default.
• W2227983549 hasAuthorship W2227983549A5035092090 @default.
• W2227983549 hasAuthorship W2227983549A5042137175 @default.
• W2227983549 hasAuthorship W2227983549A5047998886 @default.
• W2227983549 hasAuthorship W2227983549A5072076684 @default.
• W2227983549 hasAuthorship W2227983549A5089713199 @default.
• W2227983549 hasBestOaLocation W22279835491 @default.
• W2227983549 hasConcept C113196181 @default.
• W2227983549 hasConcept C119599485 @default.
• W2227983549 hasConcept C120665830 @default.
• W2227983549 hasConcept C121332964 @default.
• W2227983549 hasConcept C127413603 @default.
• W2227983549 hasConcept C132651336 @default.
• W2227983549 hasConcept C136525101 @default.
• W2227983549 hasConcept C142724271 @default.
• W2227983549 hasConcept C146978453 @default.
• W2227983549 hasConcept C159985019 @default.
• W2227983549 hasConcept C160671074 @default.
• W2227983549 hasConcept C171250308 @default.
• W2227983549 hasConcept C185592680 @default.
• W2227983549 hasConcept C192562407 @default.
• W2227983549 hasConcept C204787440 @default.
• W2227983549 hasConcept C20556612 @default.
• W2227983549 hasConcept C30403606 @default.
• W2227983549 hasConcept C43617362 @default.
• W2227983549 hasConcept C49040817 @default.
• W2227983549 hasConcept C62520636 @default.
• W2227983549 hasConcept C71924100 @default.
• W2227983549 hasConcept C8673954 @default.
• W2227983549 hasConcept C94915269 @default.
• W2227983549 hasConceptScore W2227983549C113196181 @default.
• W2227983549 hasConceptScore W2227983549C119599485 @default.
• W2227983549 hasConceptScore W2227983549C120665830 @default.
• W2227983549 hasConceptScore W2227983549C121332964 @default.
• W2227983549 hasConceptScore W2227983549C127413603 @default.
• W2227983549 hasConceptScore W2227983549C132651336 @default.
• W2227983549 hasConceptScore W2227983549C136525101 @default.
• W2227983549 hasConceptScore W2227983549C142724271 @default.
• W2227983549 hasConceptScore W2227983549C146978453 @default.

• next