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- W2228024443 abstract "Tea (Camellia sinensis L.) is the most popular, flavored, functional, and therapeutic non-alcoholic drink consumed by two-thirds of the world's population. Black tea leaves are reported to contain thousands of bioactive constituents such as polyphenols, amino acids, volatile compounds, and alkaloids that exhibit a range of promising pharmacological properties. Due to strong antioxidant property, black tea inhibits the development of various cancers by regulating oxidative damage of biomolecules, endogenous antioxidants, and pathways of mutagen and transcription of antioxidant gene pool. Regular drinking of phytochemicals-rich black tea is linked to regulate several molecular targets, including COX-2, 5-LOX, AP-1, JNK, STAT, EGFR, AKT, Bcl2, NF-κB, Bcl-xL, caspases, p53, FOXO1, TNFα, PARP, and MAPK, which may be the basis of how dose of black tea prevents and cures cancer. In vitro and preclinical studies support the anti-cancer activity of black tea; however, its effect in human trails is uncertain, although more clinical experiments are needed at molecular levels to understand its anti-cancer property. This review discusses the current knowledge on phytochemistry, chemopreventive activity, and clinical applications of black tea to reveal its anti-cancer effect." @default.
- W2228024443 created "2016-06-24" @default.
- W2228024443 creator A5026003412 @default.
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- W2228024443 creator A5065745968 @default.
- W2228024443 creator A5073648978 @default.
- W2228024443 creator A5079925280 @default.
- W2228024443 date "2017-02-21" @default.
- W2228024443 modified "2023-10-02" @default.
- W2228024443 title "Black tea: Phytochemicals, cancer chemoprevention, and clinical studies" @default.
- W2228024443 cites W1484788901 @default.
- W2228024443 cites W1562319334 @default.
- W2228024443 cites W1603661544 @default.
- W2228024443 cites W1937169612 @default.
- W2228024443 cites W1953353401 @default.
- W2228024443 cites W1967136835 @default.
- W2228024443 cites W1973981954 @default.
- W2228024443 cites W1973990109 @default.
- W2228024443 cites W1974374325 @default.
- W2228024443 cites W1983018452 @default.
- W2228024443 cites W1984846756 @default.
- W2228024443 cites W1987695888 @default.
- W2228024443 cites W1992645711 @default.
- W2228024443 cites W1996638916 @default.
- W2228024443 cites W1998412430 @default.
- W2228024443 cites W1998921522 @default.
- W2228024443 cites W2002286565 @default.
- W2228024443 cites W2003114754 @default.
- W2228024443 cites W2003895116 @default.
- W2228024443 cites W2004048796 @default.
- W2228024443 cites W2006313830 @default.
- W2228024443 cites W2008944417 @default.
- W2228024443 cites W2010719972 @default.
- W2228024443 cites W2011037048 @default.
- W2228024443 cites W2015411601 @default.
- W2228024443 cites W2017079479 @default.
- W2228024443 cites W2021947932 @default.
- W2228024443 cites W2023499379 @default.
- W2228024443 cites W2025451960 @default.
- W2228024443 cites W2026238951 @default.
- W2228024443 cites W2030359561 @default.
- W2228024443 cites W2035277609 @default.
- W2228024443 cites W2035819064 @default.
- W2228024443 cites W2036779041 @default.
- W2228024443 cites W2036844314 @default.
- W2228024443 cites W2046706222 @default.
- W2228024443 cites W2050695134 @default.
- W2228024443 cites W2052350574 @default.
- W2228024443 cites W2054882765 @default.
- W2228024443 cites W2057732608 @default.
- W2228024443 cites W2061409571 @default.
- W2228024443 cites W2061799142 @default.
- W2228024443 cites W2061975350 @default.
- W2228024443 cites W2062776400 @default.
- W2228024443 cites W2064110374 @default.
- W2228024443 cites W2068270432 @default.
- W2228024443 cites W2069084145 @default.
- W2228024443 cites W2070488306 @default.
- W2228024443 cites W2070785261 @default.
- W2228024443 cites W2072036327 @default.
- W2228024443 cites W2073260913 @default.
- W2228024443 cites W2073303759 @default.
- W2228024443 cites W2074477488 @default.
- W2228024443 cites W2075990443 @default.
- W2228024443 cites W2079949336 @default.
- W2228024443 cites W2082851306 @default.
- W2228024443 cites W2083177668 @default.
- W2228024443 cites W2086010087 @default.
- W2228024443 cites W2087936989 @default.
- W2228024443 cites W2090266496 @default.
- W2228024443 cites W2094511530 @default.
- W2228024443 cites W2096841928 @default.
- W2228024443 cites W2099795845 @default.
- W2228024443 cites W2101624663 @default.
- W2228024443 cites W2103751462 @default.
- W2228024443 cites W2105966479 @default.
- W2228024443 cites W2107921208 @default.
- W2228024443 cites W2108441239 @default.
- W2228024443 cites W2113040286 @default.
- W2228024443 cites W2113482275 @default.
- W2228024443 cites W2121005650 @default.
- W2228024443 cites W2123066677 @default.
- W2228024443 cites W2124290816 @default.
- W2228024443 cites W2129043178 @default.
- W2228024443 cites W2140573009 @default.
- W2228024443 cites W2141385781 @default.
- W2228024443 cites W2142038272 @default.
- W2228024443 cites W2143923732 @default.
- W2228024443 cites W2150015908 @default.
- W2228024443 cites W2163490818 @default.
- W2228024443 cites W2167637569 @default.
- W2228024443 cites W2169238639 @default.
- W2228024443 cites W2171972339 @default.
- W2228024443 cites W2209081542 @default.
- W2228024443 cites W33299221 @default.
- W2228024443 cites W4250344789 @default.
- W2228024443 doi "https://doi.org/10.1080/10408398.2014.994700" @default.
- W2228024443 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26561007" @default.