FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2229811452> ?p ?o ?g. }

• W2229811452 endingPage "683" @default.
• W2229811452 startingPage "674" @default.
• W2229811452 abstract "CD8(+) T cells specific to caspase-cleaved antigens derived from apoptotic T cells represent a principal player in chronic immune activation. Here, we found that both apoptotic epitope-specific and hepatitis C virus (HCV)-specific CD8(+) T cells were mostly confined within the effector memory (EM) or terminally differentiated EM CD45RA(+) cell subsets expressing a dysfunctional T-helper 1-like signature program in chronic HCV infection. However, apoptotic epitope-specific CD8(+) T cells produced tumor necrosis factor α and interleukin 2 at the intrahepatic level significantly more than HCV-specific CD8(+) T cells, despite both populations expressing high levels of programmed death 1 receptor. Contextually, only apoptotic epitope-specific CD8(+) T cells correlated with both interferon-stimulated gene levels in T cells and hepatic fibrosis score. Together, these data suggest that, compared with HCV-specific CD8(+) T cells, apoptotic epitope-specific CD8(+) T cells can better sustain chronic immune activation, owing to their capacity to produce tumor necrosis factor α, and exhibit greater resistance to inhibitory signals during chronic HCV infection." @default.
• W2229811452 created "2016-06-24" @default.
• W2229811452 creator A5001100012 @default.
• W2229811452 creator A5002613530 @default.
• W2229811452 creator A5004077074 @default.
• W2229811452 creator A5006408418 @default.
• W2229811452 creator A5007990698 @default.
• W2229811452 creator A5008417349 @default.
• W2229811452 creator A5009332815 @default.
• W2229811452 creator A5009952922 @default.
• W2229811452 creator A5010966529 @default.
• W2229811452 creator A5011566650 @default.
• W2229811452 creator A5017683155 @default.
• W2229811452 creator A5022825256 @default.
• W2229811452 creator A5027385996 @default.
• W2229811452 creator A5037285448 @default.
• W2229811452 creator A5049239605 @default.
• W2229811452 creator A5056092156 @default.
• W2229811452 creator A5056673453 @default.
• W2229811452 creator A5057663130 @default.
• W2229811452 creator A5075572192 @default.
• W2229811452 date "2015-09-19" @default.
• W2229811452 modified "2023-10-18" @default.
• W2229811452 title "Apoptotic Epitope–Specific CD8⁺T Cells and Interferon Signaling Intersect in Chronic Hepatitis C Virus Infection" @default.
• W2229811452 cites W1588348996 @default.
• W2229811452 cites W1601709990 @default.
• W2229811452 cites W1967261754 @default.
• W2229811452 cites W1977105782 @default.
• W2229811452 cites W1986269759 @default.
• W2229811452 cites W1992541741 @default.
• W2229811452 cites W1993617345 @default.
• W2229811452 cites W1998976242 @default.
• W2229811452 cites W2006904408 @default.
• W2229811452 cites W2024556668 @default.
• W2229811452 cites W2031472841 @default.
• W2229811452 cites W2031913105 @default.
• W2229811452 cites W2035830838 @default.
• W2229811452 cites W2045423123 @default.
• W2229811452 cites W2049619994 @default.
• W2229811452 cites W2049868800 @default.
• W2229811452 cites W2050466666 @default.
• W2229811452 cites W2054119257 @default.
• W2229811452 cites W2055021349 @default.
• W2229811452 cites W2056052081 @default.
• W2229811452 cites W2057499380 @default.
• W2229811452 cites W2058277625 @default.
• W2229811452 cites W2059842152 @default.
• W2229811452 cites W2075915057 @default.
• W2229811452 cites W2076268623 @default.
• W2229811452 cites W2077116159 @default.
• W2229811452 cites W2077713919 @default.
• W2229811452 cites W2087662797 @default.
• W2229811452 cites W2096764433 @default.
• W2229811452 cites W2097980930 @default.
• W2229811452 cites W2099069940 @default.
• W2229811452 cites W2099228133 @default.
• W2229811452 cites W2111359040 @default.
• W2229811452 cites W2113285371 @default.
• W2229811452 cites W2113331651 @default.
• W2229811452 cites W2113859808 @default.
• W2229811452 cites W2115889074 @default.
• W2229811452 cites W2117142918 @default.
• W2229811452 cites W2119896120 @default.
• W2229811452 cites W2128963820 @default.
• W2229811452 cites W2130259551 @default.
• W2229811452 cites W2134423857 @default.
• W2229811452 cites W2139660948 @default.
• W2229811452 cites W2144373841 @default.
• W2229811452 cites W2148864053 @default.
• W2229811452 cites W2165638318 @default.
• W2229811452 cites W2167827953 @default.
• W2229811452 cites W655110993 @default.
• W2229811452 cites W164552732 @default.
• W2229811452 doi "https://doi.org/10.1093/infdis/jiv460" @default.
• W2229811452 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26386427" @default.
• W2229811452 hasPublicationYear "2015" @default.
• W2229811452 type Work @default.
• W2229811452 sameAs 2229811452 @default.
• W2229811452 citedByCount "8" @default.
• W2229811452 countsByYear W22298114522017 @default.
• W2229811452 countsByYear W22298114522018 @default.
• W2229811452 countsByYear W22298114522019 @default.
• W2229811452 countsByYear W22298114522020 @default.
• W2229811452 countsByYear W22298114522021 @default.
• W2229811452 crossrefType "journal-article" @default.
• W2229811452 hasAuthorship W2229811452A5001100012 @default.
• W2229811452 hasAuthorship W2229811452A5002613530 @default.
• W2229811452 hasAuthorship W2229811452A5004077074 @default.
• W2229811452 hasAuthorship W2229811452A5006408418 @default.
• W2229811452 hasAuthorship W2229811452A5007990698 @default.
• W2229811452 hasAuthorship W2229811452A5008417349 @default.
• W2229811452 hasAuthorship W2229811452A5009332815 @default.
• W2229811452 hasAuthorship W2229811452A5009952922 @default.
• W2229811452 hasAuthorship W2229811452A5010966529 @default.
• W2229811452 hasAuthorship W2229811452A5011566650 @default.
• W2229811452 hasAuthorship W2229811452A5017683155 @default.
• W2229811452 hasAuthorship W2229811452A5022825256 @default.
• W2229811452 hasAuthorship W2229811452A5027385996 @default.

• next