FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2229861203> ?p ?o ?g. }

• W2229861203 endingPage "20" @default.
• W2229861203 startingPage "5" @default.
• W2229861203 abstract "To prospectively observe second-line treatment strategies, their clinical outcomes, and treatment costs in patients with glaucoma or ocular hypertension (OH) in France.Patients were recruited between 1998 and 2000 in 37 centers and were followed for up to 2 years. Outcomes were numbers of and reasons for treatment changes, changes in clinical parameters (intraocular pressure [IOP] levels, visual field defects, and optic nerve excavation), and direct medical costs associated with glaucoma management in patients receiving monotherapy or combination therapy. This article reports results of an interim analysis of 1-year follow-up data for patients having at least two contacts with a study ophthalmologist.Data were analyzed for 283 patients and 549 treated eyes. Ocular hypotensive monotherapy was used as first-line therapy in 92.0% of eyes. Second-line treatment was initiated an average of 3.4 +/- 0.5 years after diagnosis, primarily due to insufficient IOP control (62.8%). Mean IOP reductions after 1 year of second-line therapy were 3.0 mmHg in eyes treated with latanoprost monotherapy versus 2. 1 mmHg in those receiving beta-blocker monotherapy (p = 0.02) and 5.4 mmHg in eyes treated with the latanoprost + timolol combination versus 4.1 mmHg in those receiving combination therapies that did not include latanoprost (p = 0.01). Although second-line treatment with latanoprost was more costly than treatment with beta blockers, the average daily cost for latanoprost monotherapy was similar to that for patients who failed beta-blocker monotherapy, and latanoprost + timolol was less costly than therapeutic combinations without latanoprost.Insufficient IOP control is the main reason for changing first-line treatment in patients with glaucoma or OH. After 1 year, second-line treatment with latanoprost, as monotherapy or combined with timolol, provides superior IOP control at an acceptable cost." @default.
• W2229861203 created "2016-06-24" @default.
• W2229861203 creator A5047128384 @default.
• W2229861203 creator A5068512939 @default.
• W2229861203 date "2003-07-01" @default.
• W2229861203 modified "2023-10-02" @default.
• W2229861203 title "Naturalistic, Prospective Study of Glaucoma and Ocular Hypertension Treatment in France: Strategies, Clinical Outcomes, and Costs at 1 Year" @default.
• W2229861203 cites W1490909919 @default.
• W2229861203 cites W1515865864 @default.
• W2229861203 cites W1571272128 @default.
• W2229861203 cites W1996539435 @default.
• W2229861203 cites W2002911614 @default.
• W2229861203 cites W2017429090 @default.
• W2229861203 cites W2030127922 @default.
• W2229861203 cites W2058065361 @default.
• W2229861203 cites W2076260416 @default.
• W2229861203 cites W2108773276 @default.
• W2229861203 cites W2110897487 @default.
• W2229861203 cites W2120711134 @default.
• W2229861203 cites W2140594570 @default.
• W2229861203 cites W2336197566 @default.
• W2229861203 cites W2416862245 @default.
• W2229861203 cites W2462871307 @default.
• W2229861203 cites W2625521663 @default.
• W2229861203 cites W2915306323 @default.
• W2229861203 cites W2977587116 @default.
• W2229861203 doi "https://doi.org/10.1177/112067210301304s02" @default.
• W2229861203 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28221459" @default.
• W2229861203 hasPublicationYear "2003" @default.
• W2229861203 type Work @default.
• W2229861203 sameAs 2229861203 @default.
• W2229861203 citedByCount "26" @default.
• W2229861203 countsByYear W22298612032014 @default.
• W2229861203 countsByYear W22298612032017 @default.
• W2229861203 countsByYear W22298612032019 @default.
• W2229861203 countsByYear W22298612032021 @default.
• W2229861203 countsByYear W22298612032023 @default.
• W2229861203 crossrefType "journal-article" @default.
• W2229861203 hasAuthorship W2229861203A5047128384 @default.
• W2229861203 hasAuthorship W2229861203A5068512939 @default.
• W2229861203 hasConcept C118487528 @default.
• W2229861203 hasConcept C126322002 @default.
• W2229861203 hasConcept C141071460 @default.
• W2229861203 hasConcept C188816634 @default.
• W2229861203 hasConcept C2776521421 @default.
• W2229861203 hasConcept C2776740260 @default.
• W2229861203 hasConcept C2776999253 @default.
• W2229861203 hasConcept C2778073030 @default.
• W2229861203 hasConcept C2778527774 @default.
• W2229861203 hasConcept C2781092963 @default.
• W2229861203 hasConcept C535046627 @default.
• W2229861203 hasConcept C61943457 @default.
• W2229861203 hasConcept C71924100 @default.
• W2229861203 hasConceptScore W2229861203C118487528 @default.
• W2229861203 hasConceptScore W2229861203C126322002 @default.
• W2229861203 hasConceptScore W2229861203C141071460 @default.
• W2229861203 hasConceptScore W2229861203C188816634 @default.
• W2229861203 hasConceptScore W2229861203C2776521421 @default.
• W2229861203 hasConceptScore W2229861203C2776740260 @default.
• W2229861203 hasConceptScore W2229861203C2776999253 @default.
• W2229861203 hasConceptScore W2229861203C2778073030 @default.
• W2229861203 hasConceptScore W2229861203C2778527774 @default.
• W2229861203 hasConceptScore W2229861203C2781092963 @default.
• W2229861203 hasConceptScore W2229861203C535046627 @default.
• W2229861203 hasConceptScore W2229861203C61943457 @default.
• W2229861203 hasConceptScore W2229861203C71924100 @default.
• W2229861203 hasIssue "4_suppl" @default.
• W2229861203 hasLocation W22298612031 @default.
• W2229861203 hasLocation W22298612032 @default.
• W2229861203 hasOpenAccess W2229861203 @default.
• W2229861203 hasPrimaryLocation W22298612031 @default.
• W2229861203 hasRelatedWork W149337492 @default.
• W2229861203 hasRelatedWork W1965052468 @default.
• W2229861203 hasRelatedWork W2018483608 @default.
• W2229861203 hasRelatedWork W2054793874 @default.
• W2229861203 hasRelatedWork W2128225127 @default.
• W2229861203 hasRelatedWork W2128476364 @default.
• W2229861203 hasRelatedWork W2135467809 @default.
• W2229861203 hasRelatedWork W2170698422 @default.
• W2229861203 hasRelatedWork W2414936787 @default.
• W2229861203 hasRelatedWork W4385303425 @default.
• W2229861203 hasVolume "13" @default.
• W2229861203 isParatext "false" @default.
• W2229861203 isRetracted "false" @default.
• W2229861203 magId "2229861203" @default.
• W2229861203 workType "article" @default.