FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2230485943> ?p ?o ?g. }

• W2230485943 endingPage "465" @default.
• W2230485943 startingPage "455" @default.
• W2230485943 abstract "BackgroundA medical device containing the film-forming agent reticulated protein and a prebiotic mixture of vegetable oligo- and polysaccharides has been developed, recently receiving European approval as MED class III for the treatment of chronic/functional or recidivant diarrhoea due to different causes including irritable bowel syndrome (IBS). In the present paper, we evaluate a protein preparation containing these components in comparison with placebo in adult patients with diarrhoea-predominant IBS. MethodsIn a randomised, placebo-controlled, double-blind, parallel group, multicentre clinical trial, patients were randomly assigned to receive the combination of oligo- and polysaccharides and reticulated protein and placebo (four oral tablets/day for 56 days). Demographic, clinical and quality of life characteristics and presence and intensity of abdominal pain and flatulence (seven-point Likert scale) were assessed at three study visits (baseline and at 28 and 56 days). Stool emissions were recorded on the diary card using the seven-point Bristol Stool Scale. ResultsA total of 128 patients were randomised to receive either tablets containing the combination (n = 63) or placebo (n = 65). Treatment with oligo- and polysaccharides and reticulated protein was safe and well tolerated. A significant improvement in symptoms across the study was observed in patients treated with oligo- and polysaccharides and reticulated protein between visit 2 and visit 3 in abdominal pain (p = 0.0167) and flatulence (p = 0.0373). We also detected a statistically significant increase in the quality of life of patients receiving the active treatment from baseline to visit 3 (p < 0.0001). ConclusionsTreatment with oligo- and polysaccharides and reticulated protein is safe, improving IBS symptoms and quality of life of patients with diarrhoea-predominant IBS." @default.
• W2230485943 created "2016-06-24" @default.
• W2230485943 creator A5021413662 @default.
• W2230485943 creator A5041368431 @default.
• W2230485943 creator A5067289473 @default.
• W2230485943 date "2015-10-30" @default.
• W2230485943 modified "2023-09-29" @default.
• W2230485943 title "The combination of oligo- and polysaccharides and reticulated protein for the control of symptoms in patients with irritable bowel syndrome: Results of a randomised, placebo-controlled, double-blind, parallel group, multicentre clinical trial" @default.
• W2230485943 cites W1532990492 @default.
• W2230485943 cites W1683418430 @default.
• W2230485943 cites W1820755796 @default.
• W2230485943 cites W1937393830 @default.
• W2230485943 cites W1977704353 @default.
• W2230485943 cites W1979497759 @default.
• W2230485943 cites W1990998281 @default.
• W2230485943 cites W2000522468 @default.
• W2230485943 cites W2001298761 @default.
• W2230485943 cites W2002748459 @default.
• W2230485943 cites W2030581107 @default.
• W2230485943 cites W2034705777 @default.
• W2230485943 cites W2036855019 @default.
• W2230485943 cites W2040223383 @default.
• W2230485943 cites W2051832217 @default.
• W2230485943 cites W2064201279 @default.
• W2230485943 cites W2064372452 @default.
• W2230485943 cites W2065163505 @default.
• W2230485943 cites W2065909839 @default.
• W2230485943 cites W2068114187 @default.
• W2230485943 cites W2079153462 @default.
• W2230485943 cites W2094710813 @default.
• W2230485943 cites W2115618203 @default.
• W2230485943 cites W2118124134 @default.
• W2230485943 cites W2123070235 @default.
• W2230485943 cites W2130721753 @default.
• W2230485943 cites W2131905291 @default.
• W2230485943 cites W2136734369 @default.
• W2230485943 cites W2145850664 @default.
• W2230485943 cites W2150326634 @default.
• W2230485943 cites W2164155489 @default.
• W2230485943 cites W2164303950 @default.
• W2230485943 doi "https://doi.org/10.1177/2050640615615050" @default.
• W2230485943 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4924437" @default.
• W2230485943 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27403313" @default.
• W2230485943 hasPublicationYear "2015" @default.
• W2230485943 type Work @default.
• W2230485943 sameAs 2230485943 @default.
• W2230485943 citedByCount "20" @default.
• W2230485943 countsByYear W22304859432016 @default.
• W2230485943 countsByYear W22304859432017 @default.
• W2230485943 countsByYear W22304859432018 @default.
• W2230485943 countsByYear W22304859432019 @default.
• W2230485943 countsByYear W22304859432020 @default.
• W2230485943 countsByYear W22304859432021 @default.
• W2230485943 countsByYear W22304859432022 @default.
• W2230485943 crossrefType "journal-article" @default.
• W2230485943 hasAuthorship W2230485943A5021413662 @default.
• W2230485943 hasAuthorship W2230485943A5041368431 @default.
• W2230485943 hasAuthorship W2230485943A5067289473 @default.
• W2230485943 hasBestOaLocation W22304859431 @default.
• W2230485943 hasConcept C126322002 @default.
• W2230485943 hasConcept C142724271 @default.
• W2230485943 hasConcept C159110408 @default.
• W2230485943 hasConcept C168563851 @default.
• W2230485943 hasConcept C202061045 @default.
• W2230485943 hasConcept C203092338 @default.
• W2230485943 hasConcept C204787440 @default.
• W2230485943 hasConcept C27081682 @default.
• W2230485943 hasConcept C2775913212 @default.
• W2230485943 hasConcept C2776956441 @default.
• W2230485943 hasConcept C2778271842 @default.
• W2230485943 hasConcept C2779951463 @default.
• W2230485943 hasConcept C2780955771 @default.
• W2230485943 hasConcept C2991744798 @default.
• W2230485943 hasConcept C535046627 @default.
• W2230485943 hasConcept C71924100 @default.
• W2230485943 hasConcept C90924648 @default.
• W2230485943 hasConceptScore W2230485943C126322002 @default.
• W2230485943 hasConceptScore W2230485943C142724271 @default.
• W2230485943 hasConceptScore W2230485943C159110408 @default.
• W2230485943 hasConceptScore W2230485943C168563851 @default.
• W2230485943 hasConceptScore W2230485943C202061045 @default.
• W2230485943 hasConceptScore W2230485943C203092338 @default.
• W2230485943 hasConceptScore W2230485943C204787440 @default.
• W2230485943 hasConceptScore W2230485943C27081682 @default.
• W2230485943 hasConceptScore W2230485943C2775913212 @default.
• W2230485943 hasConceptScore W2230485943C2776956441 @default.
• W2230485943 hasConceptScore W2230485943C2778271842 @default.
• W2230485943 hasConceptScore W2230485943C2779951463 @default.
• W2230485943 hasConceptScore W2230485943C2780955771 @default.
• W2230485943 hasConceptScore W2230485943C2991744798 @default.
• W2230485943 hasConceptScore W2230485943C535046627 @default.
• W2230485943 hasConceptScore W2230485943C71924100 @default.
• W2230485943 hasConceptScore W2230485943C90924648 @default.
• W2230485943 hasIssue "3" @default.
• W2230485943 hasLocation W22304859431 @default.
• W2230485943 hasLocation W22304859432 @default.
• W2230485943 hasLocation W22304859433 @default.
• W2230485943 hasLocation W22304859434 @default.

• next