Matches in SemOpenAlex for { <https://semopenalex.org/work/W2230897915> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2230897915 endingPage "130" @default.
- W2230897915 startingPage "129" @default.
- W2230897915 abstract "There is increased scientific interest in the diagnosis of the antiphospholipid syndrome (APS), as therapeutic interventions can lead to substantial improvement in clinical outcome. As the clinical features of APS are far from specific, a sound laboratory method is needed to support or exclude the diagnosis. Two methods are currently used for the diagnosis of APS: (1) ELISA-based immunoassays for the detection of anticardiolipin (aCL) antibodies; and (2) clotting assays for determination of the lupus anticoagulant (LA). However, the first method is limited by a low specificity, and the second by low sensitivity. Furthermore, for both methods standardisation is unsatisfactory. Therefore, a number of new assays have been proposed as alternative or supplementary to aCL and LA tests. These include the anti-beta-2-glycoprotein I or antiprothrombin ELISAs, an ELISA utilising a phospholipid mixture, clotting assays with varying activators and assays utilising chromogenic substrates. This review presents a brief outline of APS, the autoantibodies associated with this syndrome, the basic principles of the standard assays used and a description of newer methods currently being validated." @default.
- W2230897915 created "2016-06-24" @default.
- W2230897915 creator A5003587098 @default.
- W2230897915 creator A5008926151 @default.
- W2230897915 creator A5016009056 @default.
- W2230897915 creator A5018151360 @default.
- W2230897915 creator A5036811980 @default.
- W2230897915 creator A5061443644 @default.
- W2230897915 creator A5066941256 @default.
- W2230897915 creator A5070300954 @default.
- W2230897915 creator A5073548467 @default.
- W2230897915 creator A5079071350 @default.
- W2230897915 date "2015-11-01" @default.
- W2230897915 modified "2023-09-24" @default.
- W2230897915 title "Markers of thrombotic events in autoimmune diseases: Comparison of Antiphospholipid Score (aPL-S) and Global Anti-phospholipid Syndrome Score (GAPSS)" @default.
- W2230897915 doi "https://doi.org/10.1016/j.jri.2015.09.029" @default.
- W2230897915 hasPublicationYear "2015" @default.
- W2230897915 type Work @default.
- W2230897915 sameAs 2230897915 @default.
- W2230897915 citedByCount "2" @default.
- W2230897915 countsByYear W22308979152020 @default.
- W2230897915 countsByYear W22308979152022 @default.
- W2230897915 crossrefType "journal-article" @default.
- W2230897915 hasAuthorship W2230897915A5003587098 @default.
- W2230897915 hasAuthorship W2230897915A5008926151 @default.
- W2230897915 hasAuthorship W2230897915A5016009056 @default.
- W2230897915 hasAuthorship W2230897915A5018151360 @default.
- W2230897915 hasAuthorship W2230897915A5036811980 @default.
- W2230897915 hasAuthorship W2230897915A5061443644 @default.
- W2230897915 hasAuthorship W2230897915A5066941256 @default.
- W2230897915 hasAuthorship W2230897915A5070300954 @default.
- W2230897915 hasAuthorship W2230897915A5073548467 @default.
- W2230897915 hasAuthorship W2230897915A5079071350 @default.
- W2230897915 hasConcept C126322002 @default.
- W2230897915 hasConcept C159654299 @default.
- W2230897915 hasConcept C163764329 @default.
- W2230897915 hasConcept C203014093 @default.
- W2230897915 hasConcept C2776874634 @default.
- W2230897915 hasConcept C2780022809 @default.
- W2230897915 hasConcept C71924100 @default.
- W2230897915 hasConceptScore W2230897915C126322002 @default.
- W2230897915 hasConceptScore W2230897915C159654299 @default.
- W2230897915 hasConceptScore W2230897915C163764329 @default.
- W2230897915 hasConceptScore W2230897915C203014093 @default.
- W2230897915 hasConceptScore W2230897915C2776874634 @default.
- W2230897915 hasConceptScore W2230897915C2780022809 @default.
- W2230897915 hasConceptScore W2230897915C71924100 @default.
- W2230897915 hasLocation W22308979151 @default.
- W2230897915 hasOpenAccess W2230897915 @default.
- W2230897915 hasPrimaryLocation W22308979151 @default.
- W2230897915 hasRelatedWork W165669756 @default.
- W2230897915 hasRelatedWork W1977645254 @default.
- W2230897915 hasRelatedWork W2019511528 @default.
- W2230897915 hasRelatedWork W2022289753 @default.
- W2230897915 hasRelatedWork W2069553539 @default.
- W2230897915 hasRelatedWork W2074986892 @default.
- W2230897915 hasRelatedWork W2099792460 @default.
- W2230897915 hasRelatedWork W2156299866 @default.
- W2230897915 hasRelatedWork W2319931263 @default.
- W2230897915 hasRelatedWork W2502283878 @default.
- W2230897915 hasVolume "112" @default.
- W2230897915 isParatext "false" @default.
- W2230897915 isRetracted "false" @default.
- W2230897915 magId "2230897915" @default.
- W2230897915 workType "article" @default.