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• W2232192272 abstract "The loads between adjacent vertebrae can be generalised as a single spatial force acting at the intervertebral centre of reaction. The exact position in vivo is unknown. However, in rigid body musculoskeletal models that simulate upright standing, the position is generally assumed to be located at the discs' centres of rotation. The influence of the antero-posterior position of the centre of reaction on muscle activity and joint loads remains unknown. Thus, by using an inverse dynamic model, we varied the position of the centre of reaction at L4/L5 (i), simultaneously at all lumbar levels (ii), and by optimisation at all lumbar levels (iii). Variation of the centres of reaction can considerably influence the activities of lumbar muscles and the joint forces between vertebrae. The optimisation of the position of the centre of reaction reduced the maximum lumbar muscle activity and axial joint forces at L4/L5 from 17.5% to 1.5% of the muscle strength and from 490 N to 390 N, respectively. Thus, when studying individual postures, such as for therapeutic or preventive evaluations, potential differences between the centre of reaction and the centre of rotation might influence the study results. These differences could be taken into account by sensitivity analyses." @default.
• W2232192272 created "2016-06-24" @default.
• W2232192272 creator A5024833088 @default.
• W2232192272 creator A5050992036 @default.
• W2232192272 creator A5075191891 @default.
• W2232192272 date "2016-03-01" @default.
• W2232192272 modified "2023-09-24" @default.
• W2232192272 title "Sensitivity analysis of the position of the intervertebral centres of reaction in upright standing – a musculoskeletal model investigation of the lumbar spine" @default.
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• W2232192272 doi "https://doi.org/10.1016/j.medengphy.2015.12.003" @default.
• W2232192272 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26774670" @default.
• W2232192272 hasPublicationYear "2016" @default.
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