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- W2232842743 endingPage "2136" @default.
- W2232842743 startingPage "2132" @default.
- W2232842743 abstract "Small changes in the structure of a foldamer may lead to gross changes in conformational preference. We show that the simple insertion or deletion of a single hydrogen bond by changes in pH or by photochemical deprotection is sufficient to refold a helical oligomer, interconverting M and P screw-sense preference. As a consequence of the switch, information may be transmitted to a remote catalytic site, selectively directing the formation of either of two enantiomeric products by a reaction involving 1,22-remote intermolecular asymmetric induction." @default.
- W2232842743 created "2016-06-24" @default.
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- W2232842743 date "2016-01-14" @default.
- W2232842743 modified "2023-10-13" @default.
- W2232842743 title "Refoldable Foldamers: Global Conformational Switching by Deletion or Insertion of a Single Hydrogen Bond" @default.
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- W2232842743 doi "https://doi.org/10.1002/anie.201510605" @default.
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