Matches in SemOpenAlex for { <https://semopenalex.org/work/W2233227987> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2233227987 abstract "Background: The laboratory diagnosis of tuberculosis ranges from simple microscopy, culture to complex molecular techniques. Rapid diagnosis is important since conventional techniques have limitations.Aims: To evaluate the efficacy of PCR using genus specific and species specific primers versus microscopy and culture in the diagnosis of tuberculosis in different clinical samples. Methods: A total of 125 clinical samples were processed for the detection of Mycobacterium tuberculosis by smear, culture & PCR in the diagnosis of tuberculosis.Results: The overall sensitivity, specificity, PPV and NPV of PCR were 75 %, 88%, 62.5% and 93.42% respectively. PCR done on non tuberculous patients were negative thus showing the specificity of 100%. PCR sensitivity in pulmonary & extra pulmonary clinical samples were 83.33% and 71.42% respectively a relatively higher value than other tests. Out of eight smear positive-culture positive (SP-CP) & twelve smear negative –culture positive (SN-CP) specimens, PCR detected 87.50 % & 66.66% respectively.Conclusions: This study showed that PCR can serve as a useful complement to clinical diagnosis. PCR can be useful in detecting the cases in extra pulmonary specimens which may be missed by smear & or culture. The PCR based assay cannot be used reliably alone as a sole diagnostic tool in the diagnosis of tuberculosis, it has to be performed in conjunction with microscopy & culture methods and interpreted with the clinical settings." @default.
- W2233227987 created "2016-06-24" @default.
- W2233227987 creator A5012863504 @default.
- W2233227987 creator A5035599465 @default.
- W2233227987 creator A5058833247 @default.
- W2233227987 creator A5061591829 @default.
- W2233227987 creator A5081486119 @default.
- W2233227987 creator A5091133374 @default.
- W2233227987 date "2014-02-01" @default.
- W2233227987 modified "2023-09-25" @default.
- W2233227987 title "A comprehensive comparison of pcr based assay versus microscopy & culture in the diagnosis of tuberculosis in different clinical specimens" @default.
- W2233227987 cites W11042886 @default.
- W2233227987 cites W124932162 @default.
- W2233227987 cites W1763443200 @default.
- W2233227987 cites W1912461648 @default.
- W2233227987 cites W1950784241 @default.
- W2233227987 cites W195959397 @default.
- W2233227987 cites W1968649252 @default.
- W2233227987 cites W1971761590 @default.
- W2233227987 cites W1995113016 @default.
- W2233227987 cites W2061969702 @default.
- W2233227987 cites W2117484165 @default.
- W2233227987 cites W2124148692 @default.
- W2233227987 cites W2140606215 @default.
- W2233227987 cites W2157737997 @default.
- W2233227987 cites W2405816029 @default.
- W2233227987 cites W2463608508 @default.
- W2233227987 cites W318383331 @default.
- W2233227987 cites W2410300309 @default.
- W2233227987 hasPublicationYear "2014" @default.
- W2233227987 type Work @default.
- W2233227987 sameAs 2233227987 @default.
- W2233227987 citedByCount "0" @default.
- W2233227987 crossrefType "journal-article" @default.
- W2233227987 hasAuthorship W2233227987A5012863504 @default.
- W2233227987 hasAuthorship W2233227987A5035599465 @default.
- W2233227987 hasAuthorship W2233227987A5058833247 @default.
- W2233227987 hasAuthorship W2233227987A5061591829 @default.
- W2233227987 hasAuthorship W2233227987A5081486119 @default.
- W2233227987 hasAuthorship W2233227987A5091133374 @default.
- W2233227987 hasConcept C104317684 @default.
- W2233227987 hasConcept C126322002 @default.
- W2233227987 hasConcept C142724271 @default.
- W2233227987 hasConcept C2777975735 @default.
- W2233227987 hasConcept C2779790121 @default.
- W2233227987 hasConcept C2781069245 @default.
- W2233227987 hasConcept C2908628106 @default.
- W2233227987 hasConcept C49105822 @default.
- W2233227987 hasConcept C55493867 @default.
- W2233227987 hasConcept C71924100 @default.
- W2233227987 hasConcept C86803240 @default.
- W2233227987 hasConceptScore W2233227987C104317684 @default.
- W2233227987 hasConceptScore W2233227987C126322002 @default.
- W2233227987 hasConceptScore W2233227987C142724271 @default.
- W2233227987 hasConceptScore W2233227987C2777975735 @default.
- W2233227987 hasConceptScore W2233227987C2779790121 @default.
- W2233227987 hasConceptScore W2233227987C2781069245 @default.
- W2233227987 hasConceptScore W2233227987C2908628106 @default.
- W2233227987 hasConceptScore W2233227987C49105822 @default.
- W2233227987 hasConceptScore W2233227987C55493867 @default.
- W2233227987 hasConceptScore W2233227987C71924100 @default.
- W2233227987 hasConceptScore W2233227987C86803240 @default.
- W2233227987 hasLocation W22332279871 @default.
- W2233227987 hasOpenAccess W2233227987 @default.
- W2233227987 hasPrimaryLocation W22332279871 @default.
- W2233227987 hasRelatedWork W1970168435 @default.
- W2233227987 hasRelatedWork W1996007117 @default.
- W2233227987 hasRelatedWork W2084197411 @default.
- W2233227987 hasRelatedWork W2090523783 @default.
- W2233227987 hasRelatedWork W2132316448 @default.
- W2233227987 hasRelatedWork W2135888817 @default.
- W2233227987 hasRelatedWork W2137200786 @default.
- W2233227987 hasRelatedWork W2140606215 @default.
- W2233227987 hasRelatedWork W2149780076 @default.
- W2233227987 hasRelatedWork W2163006924 @default.
- W2233227987 hasRelatedWork W2249588698 @default.
- W2233227987 hasRelatedWork W2327903859 @default.
- W2233227987 hasRelatedWork W2348487498 @default.
- W2233227987 hasRelatedWork W2386337875 @default.
- W2233227987 hasRelatedWork W2391412655 @default.
- W2233227987 hasRelatedWork W2409591937 @default.
- W2233227987 hasRelatedWork W2435131752 @default.
- W2233227987 hasRelatedWork W2615452726 @default.
- W2233227987 hasRelatedWork W262418495 @default.
- W2233227987 hasRelatedWork W1893481968 @default.
- W2233227987 isParatext "false" @default.
- W2233227987 isRetracted "false" @default.
- W2233227987 magId "2233227987" @default.
- W2233227987 workType "article" @default.