FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2233438897> ?p ?o ?g. }

• W2233438897 endingPage "194" @default.
• W2233438897 startingPage "179" @default.
• W2233438897 abstract "The esophagus is a region with three functional zones: (1) the upper esophageal sphincter; (2) the esophageal body; and (3) the lower esophageal sphincter. Control mechanisms within the central nervous system and peripherally serve to integrate these functional zones in a region where voluntary and involuntary control mechanisms and the activity of two different types of muscle are intimately coordinated. The distal 50 to 60 per cent of the esophagus in humans is entirely smooth muscle. Extrinsic control for esophageal motor function resides in a brainstem swallowing center with an afferent reception system, an efferent system of motor neurones, and a complex organizing or internuncial system of neurones. Sensory information from the esophagus is carried in the vagus nerves, but sensory pathways are also present in sympathetics entering the spinal cord. The vagus nerve receiving fibers both from the nucleus ambiguus and the dorsal motor nucleus innervates the striated and smooth muscle esophagus, respectively, including the sphincters. There is a myenteric nerve plexus in both the striated and smooth muscle segments. In the smooth muscle esophagus, there are two important effector neurones, an excitatory cholinergic neurone, and a nonadrenergic, noncholinergic (NANC) inhibitory neurone. The striated muscle contraction is directed and coordinated by sequential excitation through vagal fibers programmed by the central control mechanism. There are at least four potential control mechanisms for peristalsis in the smooth muscle esophagus: efferent motor fibers programmed by the swallowing center fire sequentially during peristalsis; the intramural neural mechanism can be excited to produce peristalsis near the onset of stimulation or with a delay after termination of stimulation; there is evidence for myogenic propagation of a peristaltic contraction. In humans, swallow-induced peristalsis is cholinergic and appears to result primarily from sequencing and activation of the intramural excitatory cholinergic neurones. Both central and peripheral levels of control are highly integrated to focus on the excitatory cholinergic neurones. It is likely that under normal circumstances, the central control mechanism exerts the dominant influence on these neurones for initiation and coordination of peristalsis in the smooth muscle esophagus. In humans, resting tone in the lower esophageal sphincter is predominantly cholinergic, but this tone is regulated by a balance between many excitatory and inhibitory influences. The relaxation on swallowing is caused by active inhibition of the muscle through NANC inhibitory neurones and cessation of tonic neural excitation to the" @default.
• W2233438897 created "2016-06-24" @default.
• W2233438897 creator A5064292555 @default.
• W2233438897 date "1989-06-01" @default.
• W2233438897 modified "2023-09-30" @default.
• W2233438897 title "Physiology of Esophageal Motor Function" @default.
• W2233438897 cites W1409010566 @default.
• W2233438897 cites W1428098757 @default.
• W2233438897 cites W1494389696 @default.
• W2233438897 cites W1590275982 @default.
• W2233438897 cites W1614409109 @default.
• W2233438897 cites W1617453810 @default.
• W2233438897 cites W1720963523 @default.
• W2233438897 cites W1788872550 @default.
• W2233438897 cites W1923799083 @default.
• W2233438897 cites W1930208819 @default.
• W2233438897 cites W1965125497 @default.
• W2233438897 cites W1973637184 @default.
• W2233438897 cites W1983049515 @default.
• W2233438897 cites W1983949398 @default.
• W2233438897 cites W1985430469 @default.
• W2233438897 cites W1998285784 @default.
• W2233438897 cites W2002668834 @default.
• W2233438897 cites W2002905540 @default.
• W2233438897 cites W2015023253 @default.
• W2233438897 cites W2019135743 @default.
• W2233438897 cites W2032217483 @default.
• W2233438897 cites W2038438852 @default.
• W2233438897 cites W2039058546 @default.
• W2233438897 cites W2057153237 @default.
• W2233438897 cites W2065270641 @default.
• W2233438897 cites W2069804739 @default.
• W2233438897 cites W2070113700 @default.
• W2233438897 cites W2084004261 @default.
• W2233438897 cites W2086960999 @default.
• W2233438897 cites W2102792440 @default.
• W2233438897 cites W2123011661 @default.
• W2233438897 cites W2150794133 @default.
• W2233438897 cites W2163376469 @default.
• W2233438897 cites W2174677354 @default.
• W2233438897 cites W2257376979 @default.
• W2233438897 cites W2268518104 @default.
• W2233438897 cites W2314286019 @default.
• W2233438897 cites W2321583985 @default.
• W2233438897 cites W2407285432 @default.
• W2233438897 cites W2411054076 @default.
• W2233438897 cites W2412654728 @default.
• W2233438897 cites W2417289800 @default.
• W2233438897 cites W2437433694 @default.
• W2233438897 cites W2512445801 @default.
• W2233438897 doi "https://doi.org/10.1016/s0889-8553(21)00674-9" @default.
• W2233438897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2668166" @default.
• W2233438897 hasPublicationYear "1989" @default.
• W2233438897 type Work @default.
• W2233438897 sameAs 2233438897 @default.
• W2233438897 citedByCount "71" @default.
• W2233438897 countsByYear W22334388972012 @default.
• W2233438897 countsByYear W22334388972013 @default.
• W2233438897 countsByYear W22334388972014 @default.
• W2233438897 countsByYear W22334388972015 @default.
• W2233438897 countsByYear W22334388972016 @default.
• W2233438897 countsByYear W22334388972019 @default.
• W2233438897 countsByYear W22334388972021 @default.
• W2233438897 countsByYear W22334388972022 @default.
• W2233438897 countsByYear W22334388972023 @default.
• W2233438897 crossrefType "journal-article" @default.
• W2233438897 hasAuthorship W2233438897A5064292555 @default.
• W2233438897 hasConcept C105702510 @default.
• W2233438897 hasConcept C112497637 @default.
• W2233438897 hasConcept C112592302 @default.
• W2233438897 hasConcept C126322002 @default.
• W2233438897 hasConcept C141071460 @default.
• W2233438897 hasConcept C169760540 @default.
• W2233438897 hasConcept C17077164 @default.
• W2233438897 hasConcept C204232928 @default.
• W2233438897 hasConcept C206813253 @default.
• W2233438897 hasConcept C24998067 @default.
• W2233438897 hasConcept C2776512019 @default.
• W2233438897 hasConcept C2776752467 @default.
• W2233438897 hasConcept C2776907353 @default.
• W2233438897 hasConcept C2777819096 @default.
• W2233438897 hasConcept C2778110749 @default.
• W2233438897 hasConcept C2779263132 @default.
• W2233438897 hasConcept C2779958274 @default.
• W2233438897 hasConcept C2780775167 @default.
• W2233438897 hasConcept C2780866171 @default.
• W2233438897 hasConcept C2781404750 @default.
• W2233438897 hasConcept C2909432713 @default.
• W2233438897 hasConcept C529278444 @default.
• W2233438897 hasConcept C71924100 @default.
• W2233438897 hasConcept C86803240 @default.
• W2233438897 hasConceptScore W2233438897C105702510 @default.
• W2233438897 hasConceptScore W2233438897C112497637 @default.
• W2233438897 hasConceptScore W2233438897C112592302 @default.
• W2233438897 hasConceptScore W2233438897C126322002 @default.
• W2233438897 hasConceptScore W2233438897C141071460 @default.
• W2233438897 hasConceptScore W2233438897C169760540 @default.
• W2233438897 hasConceptScore W2233438897C17077164 @default.

• next