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• W2233507925 abstract "The association between man and microorganism started during the early stages of human evolution. It is therefore of no surprise that the concept of bacteria influencing human development is of significance. In spite of this, evidence that bacteria may influenceaspecifichost’sdevelopmenthaslargelybeenderivedfromresearchfindings obtained from invertebrate models. Nevertheless, the initial findings generated from these invertebrate models may have some relevance to both animal and human development. For example, research has shown that bacteria, such as Vibrio fischeri, are capable of affecting morphological changes in the marine squid Euprymna scolopes. The ‘commensal’ relationship between V. fischeri and E. scolopes occurs when the squid hatches from its eggs. As the eggs hatch, within a few hours, V. fischeri, located in the sea water, colonize the newly formed squid. V. fischeri are then thought to induce morphological changes in the developing light organ of the squid, brought about by diffusible communication signals released by the bacteria. Although the communication between bacteria and the mammalian cells was first studied in the ‘vibrio‐squid model’, the theory and science behind this is thought to have direct relevance to infections and diseases in humans. This would therefore indicate some degree of organization and co-ordination at the molecular level which may be applicable to human development. As bacteria do play a role in human development, it is probable that bacteria contribute significantly to human ageing. In fact, evidence for this has been documented in germ-free mice, wherein the mice had been infected with Bacteroides thetaiotaomicron. Bacteroides were found to affect the expression of various host genes known to have an influence on things such as nutrient uptake, metabolism, angiogenesis, mucosal barrier function," @default.
• W2233507925 created "2016-06-24" @default.
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• W2233507925 date "2009-01-01" @default.
• W2233507925 modified "2023-09-24" @default.
• W2233507925 title "Indigenous Microbiota and Association with the Host" @default.
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• W2233507925 doi "https://doi.org/10.1007/978-1-59745-327-1_2" @default.
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