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- W2233652008 abstract "Publisher Summary 5-Methoxyindoles are synthesised.in the pineal gland and two of them, melatonin and 5-methoxytryptophol (ML) have been shown to be antigonadotrophic. However, it is uncertain whether they directly suppress gonadal hormones secretion or act, instead, by inhibiting the release of pituitary gonadotrophins. Recently, the development of a sensitive and specific assay for ML has allowed measuring this indole in the circulation. The changes in concentration of ML during the human menstrual cycle have been investigated and these findings were related to the circulating levels of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). In addition, changes in concentration of ML provoked by an insulin-induced hypoglycaemic stress test have been measured and these changes were related to the stimulus of pituitary hormones induced by the test." @default.
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- W2233652008 date "1979-01-01" @default.
- W2233652008 modified "2023-09-27" @default.
- W2233652008 title "5-Methoxytryptophol and Pituitary Function in Man" @default.
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- W2233652008 doi "https://doi.org/10.1016/s0079-6123(08)62957-x" @default.
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