Matches in SemOpenAlex for { <https://semopenalex.org/work/W2233799670> ?p ?o ?g. }
- W2233799670 endingPage "39" @default.
- W2233799670 startingPage "31" @default.
- W2233799670 abstract "Tissue-engineered biologic products may be a viable option in the reconstruction of pelvic organ prolapse (POP). This study was based on the hypothesis that human adipose-derived stem cells (hASCs) are viable in acellular bovine pericardium (ABP), when reseeded by two different techniques, and thus, aid in the reconstruction. To investigate the reseeding of hASCs on ABP grafts by using non-invasive bioluminescence imaging (BLI), and to identify the effective hASCs-scaffold combinations that enabled regeneration. Thirty female athymic nude mice were randomly divided into three groups: In the VIVO group, ABPs were implanted in the subcutaneous pockets and enhanced green fluorescent protein luciferase (eGFP·Luc)-hASCs (1 × 10(6) cells/50 µL) were injected on the ABP at the same time. In the VITRO group, the mice were implanted with grafts that ABP were co-cultured with eGFP·Luc-hASCs in vitro. The BLANK group mice were implanted with ABP only. The eGFP·Luc-hASCs reseeded on ABP were analyzed by BLI, histology, and immunohistochemistry. The eGFP·Luc-hASCs reseeded on ABP could be visualized at 12 weeks in vivo. Histology revealed that the VIVO group displayed the highest cell ingrowths, small vessels, and percent of collagen content per unit area. Desmin and α-smooth muscle actin were positive at the same site in the VIVO group cells. However, few smooth muscles were observed in the VITRO and BLANK groups. These results suggest that hASCs reseeded on ABP in vivo during surgery may further enhance the properties of ABP and may promote regeneration at the recipient site, resulting in a promising treatment option for POP." @default.
- W2233799670 created "2016-06-24" @default.
- W2233799670 creator A5028518606 @default.
- W2233799670 creator A5030037458 @default.
- W2233799670 creator A5030191263 @default.
- W2233799670 creator A5036814987 @default.
- W2233799670 creator A5039044405 @default.
- W2233799670 creator A5039825678 @default.
- W2233799670 date "2015-08-07" @default.
- W2233799670 modified "2023-10-16" @default.
- W2233799670 title "<i>In vivo</i> effects of human adipose-derived stem cells reseeding on acellular bovine pericardium in nude mice" @default.
- W2233799670 cites W1537450204 @default.
- W2233799670 cites W1966870269 @default.
- W2233799670 cites W1972678839 @default.
- W2233799670 cites W1980123114 @default.
- W2233799670 cites W1982050295 @default.
- W2233799670 cites W1982632226 @default.
- W2233799670 cites W2006606496 @default.
- W2233799670 cites W2021634519 @default.
- W2233799670 cites W2022078476 @default.
- W2233799670 cites W2025371271 @default.
- W2233799670 cites W2039140682 @default.
- W2233799670 cites W2045343492 @default.
- W2233799670 cites W2066216354 @default.
- W2233799670 cites W2079626763 @default.
- W2233799670 cites W2083874638 @default.
- W2233799670 cites W2113974537 @default.
- W2233799670 cites W2148419063 @default.
- W2233799670 cites W2173497140 @default.
- W2233799670 cites W2417705823 @default.
- W2233799670 cites W2605187236 @default.
- W2233799670 doi "https://doi.org/10.1177/1535370215597193" @default.
- W2233799670 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4935429" @default.
- W2233799670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26253192" @default.
- W2233799670 hasPublicationYear "2015" @default.
- W2233799670 type Work @default.
- W2233799670 sameAs 2233799670 @default.
- W2233799670 citedByCount "6" @default.
- W2233799670 countsByYear W22337996702018 @default.
- W2233799670 countsByYear W22337996702019 @default.
- W2233799670 crossrefType "journal-article" @default.
- W2233799670 hasAuthorship W2233799670A5028518606 @default.
- W2233799670 hasAuthorship W2233799670A5030037458 @default.
- W2233799670 hasAuthorship W2233799670A5030191263 @default.
- W2233799670 hasAuthorship W2233799670A5036814987 @default.
- W2233799670 hasAuthorship W2233799670A5039044405 @default.
- W2233799670 hasAuthorship W2233799670A5039825678 @default.
- W2233799670 hasBestOaLocation W22337996702 @default.
- W2233799670 hasConcept C105702510 @default.
- W2233799670 hasConcept C111335760 @default.
- W2233799670 hasConcept C134018914 @default.
- W2233799670 hasConcept C142724271 @default.
- W2233799670 hasConcept C147447768 @default.
- W2233799670 hasConcept C150903083 @default.
- W2233799670 hasConcept C161997846 @default.
- W2233799670 hasConcept C16685009 @default.
- W2233799670 hasConcept C171056886 @default.
- W2233799670 hasConcept C171089720 @default.
- W2233799670 hasConcept C185592680 @default.
- W2233799670 hasConcept C202751555 @default.
- W2233799670 hasConcept C204232928 @default.
- W2233799670 hasConcept C207001950 @default.
- W2233799670 hasConcept C26291073 @default.
- W2233799670 hasConcept C2779072444 @default.
- W2233799670 hasConcept C28328180 @default.
- W2233799670 hasConcept C54009773 @default.
- W2233799670 hasConcept C54355233 @default.
- W2233799670 hasConcept C55493867 @default.
- W2233799670 hasConcept C57742111 @default.
- W2233799670 hasConcept C71924100 @default.
- W2233799670 hasConcept C81885089 @default.
- W2233799670 hasConcept C86803240 @default.
- W2233799670 hasConcept C95444343 @default.
- W2233799670 hasConceptScore W2233799670C105702510 @default.
- W2233799670 hasConceptScore W2233799670C111335760 @default.
- W2233799670 hasConceptScore W2233799670C134018914 @default.
- W2233799670 hasConceptScore W2233799670C142724271 @default.
- W2233799670 hasConceptScore W2233799670C147447768 @default.
- W2233799670 hasConceptScore W2233799670C150903083 @default.
- W2233799670 hasConceptScore W2233799670C161997846 @default.
- W2233799670 hasConceptScore W2233799670C16685009 @default.
- W2233799670 hasConceptScore W2233799670C171056886 @default.
- W2233799670 hasConceptScore W2233799670C171089720 @default.
- W2233799670 hasConceptScore W2233799670C185592680 @default.
- W2233799670 hasConceptScore W2233799670C202751555 @default.
- W2233799670 hasConceptScore W2233799670C204232928 @default.
- W2233799670 hasConceptScore W2233799670C207001950 @default.
- W2233799670 hasConceptScore W2233799670C26291073 @default.
- W2233799670 hasConceptScore W2233799670C2779072444 @default.
- W2233799670 hasConceptScore W2233799670C28328180 @default.
- W2233799670 hasConceptScore W2233799670C54009773 @default.
- W2233799670 hasConceptScore W2233799670C54355233 @default.
- W2233799670 hasConceptScore W2233799670C55493867 @default.
- W2233799670 hasConceptScore W2233799670C57742111 @default.
- W2233799670 hasConceptScore W2233799670C71924100 @default.
- W2233799670 hasConceptScore W2233799670C81885089 @default.
- W2233799670 hasConceptScore W2233799670C86803240 @default.
- W2233799670 hasConceptScore W2233799670C95444343 @default.