Matches in SemOpenAlex for { <https://semopenalex.org/work/W2234104629> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2234104629 abstract "Background Research consistently suggests that compared to singletons, twins are at increased risk of congenital anomalies. The risk of congenital anomalies amongst twins that share a placenta, monochorionic (MC) twins, reportedly exceeds that of twins that do not share a placenta, dichorionic (DC) twins. However, the risk of congenital heart disease (CHD) amongst twins is less well researched, particularly in relation to chorionicity. The aim of this study was to calculate the risk of CHD in twins and to examine the relative risk (RR) of CHD in twins compared to singletons, according to chorionicity and CHD severity. Methods Twins and singletons with CHD notified to the Northern Congenital Abnormality Survey (NorCAS) between 1998–2010 formed this population-based register study. Information on chorionicity was obtained from the Northern Survey of Twins and Multiple Pregnancy. The percentage of live births and stillbirths in the population that occurred with CHD (either in live births, fetal deaths (≥20 weeks gestation) or terminations of pregnancy for fetal anomaly) was calculated for twins and singletons. Similarly, the percentage of twin pregnancies associated with at least one case of CHD was calculated. The RR of CHD in twins compared to singletons was estimated using Poisson regression. Cases with extra-cardiac anomalies were excluded. Results There were 399,414 singleton births of which 2,984 (0.7%) had CHD. Among 11,871 twin births, there were 154 (1.3%) cases of CHD, meaning at least one twin was affected by CHD in 2.5% of twin pregnancies. Of 8,605 DC births and 2,317 MC births, there were 96 (1.1%) and 47 (2.0%) cases of CHD, respectively. Compared to singletons, twins were at 73% significant increased risk of CHD (RR = 1.73, 95% CI: 1.48–2.04; p Conclusion In 2.5% of twin pregnancies, at least one twin was affected by CHD. Compared to singletons, twins were at 73% increased risk of CHD, the risk being substantially higher amongst MC twins. The risk of severe CHD was particularly high in MC twins compared to singletons. This information is important for health professionals when counselling women with a twin pregnancy." @default.
- W2234104629 created "2016-06-24" @default.
- W2234104629 creator A5062603106 @default.
- W2234104629 creator A5074552203 @default.
- W2234104629 date "2015-08-31" @default.
- W2234104629 modified "2023-09-27" @default.
- W2234104629 title "OP28 Twins are at increased risk of congenital heart disease: a population-based study" @default.
- W2234104629 doi "https://doi.org/10.1136/jech-2015-206256.28" @default.
- W2234104629 hasPublicationYear "2015" @default.
- W2234104629 type Work @default.
- W2234104629 sameAs 2234104629 @default.
- W2234104629 citedByCount "0" @default.
- W2234104629 crossrefType "journal-article" @default.
- W2234104629 hasAuthorship W2234104629A5062603106 @default.
- W2234104629 hasAuthorship W2234104629A5074552203 @default.
- W2234104629 hasConcept C117354338 @default.
- W2234104629 hasConcept C126322002 @default.
- W2234104629 hasConcept C131872663 @default.
- W2234104629 hasConcept C172680121 @default.
- W2234104629 hasConcept C187212893 @default.
- W2234104629 hasConcept C2778853074 @default.
- W2234104629 hasConcept C2779234561 @default.
- W2234104629 hasConcept C2780074459 @default.
- W2234104629 hasConcept C2908647359 @default.
- W2234104629 hasConcept C2909855057 @default.
- W2234104629 hasConcept C44249647 @default.
- W2234104629 hasConcept C46973012 @default.
- W2234104629 hasConcept C54355233 @default.
- W2234104629 hasConcept C71924100 @default.
- W2234104629 hasConcept C73269764 @default.
- W2234104629 hasConcept C82789193 @default.
- W2234104629 hasConcept C86803240 @default.
- W2234104629 hasConcept C99454951 @default.
- W2234104629 hasConceptScore W2234104629C117354338 @default.
- W2234104629 hasConceptScore W2234104629C126322002 @default.
- W2234104629 hasConceptScore W2234104629C131872663 @default.
- W2234104629 hasConceptScore W2234104629C172680121 @default.
- W2234104629 hasConceptScore W2234104629C187212893 @default.
- W2234104629 hasConceptScore W2234104629C2778853074 @default.
- W2234104629 hasConceptScore W2234104629C2779234561 @default.
- W2234104629 hasConceptScore W2234104629C2780074459 @default.
- W2234104629 hasConceptScore W2234104629C2908647359 @default.
- W2234104629 hasConceptScore W2234104629C2909855057 @default.
- W2234104629 hasConceptScore W2234104629C44249647 @default.
- W2234104629 hasConceptScore W2234104629C46973012 @default.
- W2234104629 hasConceptScore W2234104629C54355233 @default.
- W2234104629 hasConceptScore W2234104629C71924100 @default.
- W2234104629 hasConceptScore W2234104629C73269764 @default.
- W2234104629 hasConceptScore W2234104629C82789193 @default.
- W2234104629 hasConceptScore W2234104629C86803240 @default.
- W2234104629 hasConceptScore W2234104629C99454951 @default.
- W2234104629 hasLocation W22341046291 @default.
- W2234104629 hasOpenAccess W2234104629 @default.
- W2234104629 hasPrimaryLocation W22341046291 @default.
- W2234104629 hasRelatedWork W1975626093 @default.
- W2234104629 hasRelatedWork W1978819153 @default.
- W2234104629 hasRelatedWork W1987683608 @default.
- W2234104629 hasRelatedWork W2000459063 @default.
- W2234104629 hasRelatedWork W2092586126 @default.
- W2234104629 hasRelatedWork W2098112108 @default.
- W2234104629 hasRelatedWork W2101410099 @default.
- W2234104629 hasRelatedWork W2133633803 @default.
- W2234104629 hasRelatedWork W2140540722 @default.
- W2234104629 hasRelatedWork W2148526184 @default.
- W2234104629 hasRelatedWork W2168676790 @default.
- W2234104629 hasRelatedWork W2196156925 @default.
- W2234104629 hasRelatedWork W2322712563 @default.
- W2234104629 hasRelatedWork W2341270908 @default.
- W2234104629 hasRelatedWork W2379564924 @default.
- W2234104629 hasRelatedWork W2405782959 @default.
- W2234104629 hasRelatedWork W2416465198 @default.
- W2234104629 hasRelatedWork W2587693215 @default.
- W2234104629 hasRelatedWork W2593929477 @default.
- W2234104629 hasRelatedWork W3030867402 @default.
- W2234104629 isParatext "false" @default.
- W2234104629 isRetracted "false" @default.
- W2234104629 magId "2234104629" @default.
- W2234104629 workType "article" @default.