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- W223417095 abstract "Obesity, which is increasing over the world, is a significant risk for lifestyle related diseases, especially type 2 diabetes. Recent studies suggest an association between obesity and periodontal disease, both of which are prevalent world-wide. The number of such studies has increased in the last 10 years, which impresses upon us that periodontal diseases are associated with obesity and metabolic syndrome, although the causality is not clear at present. On the other hand, periodontal disease is thought to affect the glucose condition of diabetic patients, and several recent studies have indicated that periodontal disease is one of the risk factors for type 2 diabetes. If there exists a direct association between obesity and periodontal disease, then a triangular relationship between obesity, diabetes, and periodontal disease may emerge. To clarify this, we started research on adipokines which are bioactive substances secreted from adipose tissues. Among several adipokines, the serum levels of resistin, which is thought to be associated with diabetes and arteriosclerosis, were elevated in subjects with periodontitis. In this review article, we summarize reports on the relationship between obesity and periodontal disease and studies on the relationship between adipokines and periodontal disease." @default.
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- W223417095 date "2011-03-01" @default.
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- W223417095 title "Obesity and oral health" @default.
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