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- W2234505572 abstract "Goal of this case series was to describe the management of Status epilepticus in dogs and cats with the aid of continuous electroencephalographic (EEG) monitoring. Ten patients (7 dogs, 3 cats) with SE of differing etiology (idiopathic epilepsy, n=3; toxicity, n=4; meningoencephalitis, n=2; undefined, n=1) were included in the study. The EEG was recorded continuously from five stainless steel needle-electrodes inserted subcutaneously. Animals were treated with diazepam and phenobarbital followed by either propofol (n=3) or pentobarbital (n=7) at a continuous rate of infusion.Clinical seizures stopped after induction of anesthesia in each animal. The EEG, however, still showed distinct epileptiform patterns (spikes, polyspikes) in all animals. Paroxysms were suppressed by increasing the infusion rate of either pentobarbital or propofol. A burst-suppression pattern was achieved in 5 animals. Electroencephalographic epileptiform activity reappeared in 4 animals when attempting to taper the dose after > 6 hours of anesthesia. This was interpreted as ongoing EEG seizure activity and an increased risk for clinical seizures, and the anesthetic dosage was adjusted accordingly. We conclude that continuous EEG monitoring appears to be a useful tool for therapeutic monitoring of SE in dogs and cats. It allows the detection of EEG seizures without the appearance of clinical seizures. Further investigations with blinded investigators and homogeneous animal groups to define therapeutic endpoints are warranted." @default.
- W2234505572 created "2016-06-24" @default.
- W2234505572 creator A5018633459 @default.
- W2234505572 date "2010-07-24" @default.
- W2234505572 modified "2023-09-26" @default.
- W2234505572 title "Kontinuierliche EEG Überwachung für die Therapie von Hunden und Katzen im Status epilepticus" @default.
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