Matches in SemOpenAlex for { <https://semopenalex.org/work/W2235003432> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2235003432 endingPage "2386" @default.
- W2235003432 startingPage "2383" @default.
- W2235003432 abstract "Objective: Blood transfusion saves lives but may also increase the risk of injury. The objective of this review was to evaluate the possible adverse effects related to transfusion of red blood cell (RBC) concentrates stored for prolonged periods. Data Sources: The data used in this review were mainly from PubMed articles published in English up to February 2015. Study Selection: Clinical and basic research articles were selected according to their relevance to this topic. Results: The ex vivo changes to RBC that occur during storage are collectively called storage lesion. It is still inconclusive if transfusion of RBC with storage lesion has clinical relevance. Multiple ongoing prospective randomized controlled trials are aimed to clarify this clinical issue. It was observed that the adverse events related to stored RBC transfusion were prominent in certain patient populations, including trauma, critical care, pediatric, and cardiac surgery patients, which leads to the investigation of underlying mechanisms. It is demonstrated that free hemoglobin toxicity, decreasing of nitric oxide bioavailability, and free iron-induced increasing of inflammation may play an important role in this process. Conclusion: It is still unclear whether transfusion of older RBC has adverse effects, and if so, which factors determine such clinical effects. However, considering the magnitude of transfusion and the widespread medical significance, potential preventive strategies should be considered, especially for the susceptible recipients." @default.
- W2235003432 created "2016-06-24" @default.
- W2235003432 creator A5016631374 @default.
- W2235003432 creator A5056774831 @default.
- W2235003432 date "2015-09-05" @default.
- W2235003432 modified "2023-10-14" @default.
- W2235003432 title "Perioperative Red Blood Cell Transfusion" @default.
- W2235003432 cites W1539918671 @default.
- W2235003432 cites W1898221764 @default.
- W2235003432 cites W1949434538 @default.
- W2235003432 cites W1967872106 @default.
- W2235003432 cites W1971939824 @default.
- W2235003432 cites W1972511528 @default.
- W2235003432 cites W1987395794 @default.
- W2235003432 cites W1990715776 @default.
- W2235003432 cites W1994720669 @default.
- W2235003432 cites W2013291317 @default.
- W2235003432 cites W2020218579 @default.
- W2235003432 cites W2024374770 @default.
- W2235003432 cites W2026862976 @default.
- W2235003432 cites W2028790836 @default.
- W2235003432 cites W2030387325 @default.
- W2235003432 cites W2035934312 @default.
- W2235003432 cites W2052065082 @default.
- W2235003432 cites W2068407547 @default.
- W2235003432 cites W2072596033 @default.
- W2235003432 cites W2094517828 @default.
- W2235003432 cites W2104073375 @default.
- W2235003432 cites W2107921622 @default.
- W2235003432 cites W2142113477 @default.
- W2235003432 cites W2146859060 @default.
- W2235003432 cites W2160016599 @default.
- W2235003432 cites W2186484798 @default.
- W2235003432 cites W2419493157 @default.
- W2235003432 doi "https://doi.org/10.4103/0366-6999.163384" @default.
- W2235003432 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4733804" @default.
- W2235003432 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26315088" @default.
- W2235003432 hasPublicationYear "2015" @default.
- W2235003432 type Work @default.
- W2235003432 sameAs 2235003432 @default.
- W2235003432 citedByCount "5" @default.
- W2235003432 countsByYear W22350034322016 @default.
- W2235003432 countsByYear W22350034322017 @default.
- W2235003432 countsByYear W22350034322018 @default.
- W2235003432 countsByYear W22350034322020 @default.
- W2235003432 countsByYear W22350034322023 @default.
- W2235003432 crossrefType "journal-article" @default.
- W2235003432 hasAuthorship W2235003432A5016631374 @default.
- W2235003432 hasAuthorship W2235003432A5056774831 @default.
- W2235003432 hasBestOaLocation W22350034321 @default.
- W2235003432 hasConcept C126322002 @default.
- W2235003432 hasConcept C141071460 @default.
- W2235003432 hasConcept C177713679 @default.
- W2235003432 hasConcept C197934379 @default.
- W2235003432 hasConcept C2776557347 @default.
- W2235003432 hasConcept C2779792907 @default.
- W2235003432 hasConcept C2780014101 @default.
- W2235003432 hasConcept C31174226 @default.
- W2235003432 hasConcept C42219234 @default.
- W2235003432 hasConcept C535046627 @default.
- W2235003432 hasConcept C63363279 @default.
- W2235003432 hasConcept C71924100 @default.
- W2235003432 hasConceptScore W2235003432C126322002 @default.
- W2235003432 hasConceptScore W2235003432C141071460 @default.
- W2235003432 hasConceptScore W2235003432C177713679 @default.
- W2235003432 hasConceptScore W2235003432C197934379 @default.
- W2235003432 hasConceptScore W2235003432C2776557347 @default.
- W2235003432 hasConceptScore W2235003432C2779792907 @default.
- W2235003432 hasConceptScore W2235003432C2780014101 @default.
- W2235003432 hasConceptScore W2235003432C31174226 @default.
- W2235003432 hasConceptScore W2235003432C42219234 @default.
- W2235003432 hasConceptScore W2235003432C535046627 @default.
- W2235003432 hasConceptScore W2235003432C63363279 @default.
- W2235003432 hasConceptScore W2235003432C71924100 @default.
- W2235003432 hasIssue "17" @default.
- W2235003432 hasLocation W22350034321 @default.
- W2235003432 hasLocation W22350034322 @default.
- W2235003432 hasLocation W22350034323 @default.
- W2235003432 hasLocation W22350034324 @default.
- W2235003432 hasLocation W22350034325 @default.
- W2235003432 hasOpenAccess W2235003432 @default.
- W2235003432 hasPrimaryLocation W22350034321 @default.
- W2235003432 hasRelatedWork W2004765186 @default.
- W2235003432 hasRelatedWork W2027915343 @default.
- W2235003432 hasRelatedWork W2276814348 @default.
- W2235003432 hasRelatedWork W2329500914 @default.
- W2235003432 hasRelatedWork W2361890743 @default.
- W2235003432 hasRelatedWork W2460979278 @default.
- W2235003432 hasRelatedWork W3122027477 @default.
- W2235003432 hasRelatedWork W3208072607 @default.
- W2235003432 hasRelatedWork W4207015735 @default.
- W2235003432 hasRelatedWork W4317433590 @default.
- W2235003432 hasVolume "128" @default.
- W2235003432 isParatext "false" @default.
- W2235003432 isRetracted "false" @default.
- W2235003432 magId "2235003432" @default.
- W2235003432 workType "article" @default.