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• W2235173651 endingPage "13" @default.
• W2235173651 startingPage "1" @default.
• W2235173651 abstract "One of the best studied systems for mammalian chromatin remodeling is transcriptional regulation during T cell development. The variety of these studies have led to important findings in T cell gene regulation and cell fate determination. Importantly, these findings have also advanced our knowledge of the function of remodeling enzymes in mammalian gene regulation. First we briefly present biochemical and cell-free analysis of 3 types of ATP dependent remodeling enzymes (SWI/SNF, Mi2, and ISWI) to construct an intellectual framework to understand how these enzymes might be working. Second, we compare and contrast the function of these enzymes during early (thymic) and late (peripheral) T cell development. Finally, we examine some of the gaps in our present understanding." @default.
• W2235173651 created "2016-06-24" @default.
• W2235173651 creator A5005572019 @default.
• W2235173651 creator A5050341725 @default.
• W2235173651 date "2012-02-01" @default.
• W2235173651 modified "2023-09-27" @default.
• W2235173651 title "ATP-dependent chromatin remodeling in T cells¹This article is part of Special Issue entitled Asilomar Chromatin and has undergone the Journal’s usual peer review process." @default.
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