FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2235596102> ?p ?o ?g. }

• W2235596102 endingPage "537" @default.
• W2235596102 startingPage "529" @default.
• W2235596102 abstract "Although herpes simplex virus type-1 (HSV-1), and type-2 (HSV-2), Staphylococcus aureus and Candida albicans co-habit the oral and genital mucosa, their interaction is poorly understood. We determined the effect HSV has on bacterial and/or fungal adherence, the initial step in biofilm formation. HeLa229 cells were infected with HSV-1 (KOS) gL86 or HSV-2 (KOS) 333gJ − at a multiplicity of infection (MOI) of 50 and 10. S. aureus (ATCC 25923) and/or C. albicans (yeast forms or germ tube forms) were co-incubated for 30 min (37 °C; 5 % CO2; 5:1 organism: HeLa cell ratio; n = 16) with virus-infected HeLa cells or uninfected HeLa cell controls. Post-incubation, the monolayers were washed (3x; PBS), lysed (RIPA), and the lysate plated onto Fungisel and/or mannitol salts agar for standard colony count. The level of HeLa-associated S. aureus was significantly decreased (P < 0.05) for both HSV-1- and HSV-2-infected cells, as compared to virus-free HeLa cell controls (38 and 59 % of control, respectively). In contrast, HSV-1 and HSV-2 significantly (P < 0.05) enhanced HeLa cell association of C. albicans yeast forms and germ tube approximately two-fold, respectively. The effect of S. aureus on germ tube and yeast form adherence to HSV-1- and HSV-2-infected cells was specific for the Candida phenotype tested. Our study suggests that HSV, while antagonist towards S. aureus adherence enhances Candida adherence. Furthermore, the combination of the three pathogens results in S. aureus adherence that is either unaffected, or partially restored depending on both the herpes viral species and the fungal phenotype present." @default.
• W2235596102 created "2016-06-24" @default.
• W2235596102 creator A5023432627 @default.
• W2235596102 creator A5024063163 @default.
• W2235596102 creator A5030106269 @default.
• W2235596102 creator A5065970650 @default.
• W2235596102 date "2016-01-13" @default.
• W2235596102 modified "2023-09-25" @default.
• W2235596102 title "Herpes Simplex Virus (HSV) Modulation of Staphylococcus aureus and Candida albicans Initiation of HeLa 299 Cell-Associated Biofilm" @default.
• W2235596102 cites W1596906634 @default.
• W2235596102 cites W1601043329 @default.
• W2235596102 cites W1897461670 @default.
• W2235596102 cites W1929223262 @default.
• W2235596102 cites W1950566269 @default.
• W2235596102 cites W1955515831 @default.
• W2235596102 cites W1967367648 @default.
• W2235596102 cites W1974322322 @default.
• W2235596102 cites W1976603454 @default.
• W2235596102 cites W1976876715 @default.
• W2235596102 cites W1978637171 @default.
• W2235596102 cites W1979385877 @default.
• W2235596102 cites W1979851989 @default.
• W2235596102 cites W1980111370 @default.
• W2235596102 cites W1994305853 @default.
• W2235596102 cites W1998732462 @default.
• W2235596102 cites W2009522209 @default.
• W2235596102 cites W2012863230 @default.
• W2235596102 cites W2015161294 @default.
• W2235596102 cites W2016239796 @default.
• W2235596102 cites W2022149895 @default.
• W2235596102 cites W2029443369 @default.
• W2235596102 cites W2030471534 @default.
• W2235596102 cites W2031935322 @default.
• W2235596102 cites W2033093592 @default.
• W2235596102 cites W2034525382 @default.
• W2235596102 cites W2035233172 @default.
• W2235596102 cites W2039182660 @default.
• W2235596102 cites W2045021209 @default.
• W2235596102 cites W2047565931 @default.
• W2235596102 cites W2049958615 @default.
• W2235596102 cites W2050094093 @default.
• W2235596102 cites W2051542157 @default.
• W2235596102 cites W2054578983 @default.
• W2235596102 cites W2059790365 @default.
• W2235596102 cites W2064735381 @default.
• W2235596102 cites W2075478958 @default.
• W2235596102 cites W2080289165 @default.
• W2235596102 cites W2084846800 @default.
• W2235596102 cites W2084978938 @default.
• W2235596102 cites W2086268256 @default.
• W2235596102 cites W2087882406 @default.
• W2235596102 cites W2088017097 @default.
• W2235596102 cites W2091067545 @default.
• W2235596102 cites W2095159928 @default.
• W2235596102 cites W2103799956 @default.
• W2235596102 cites W2114462833 @default.
• W2235596102 cites W2115911672 @default.
• W2235596102 cites W2119902364 @default.
• W2235596102 cites W2128677388 @default.
• W2235596102 cites W2135291485 @default.
• W2235596102 cites W2136221378 @default.
• W2235596102 cites W2136484902 @default.
• W2235596102 cites W2136565720 @default.
• W2235596102 cites W2137911414 @default.
• W2235596102 cites W2142761181 @default.
• W2235596102 cites W2144064375 @default.
• W2235596102 cites W2144288685 @default.
• W2235596102 cites W2146376600 @default.
• W2235596102 cites W2148805755 @default.
• W2235596102 cites W2149415083 @default.
• W2235596102 cites W2149707874 @default.
• W2235596102 cites W2154726646 @default.
• W2235596102 cites W2159812000 @default.
• W2235596102 cites W2163920778 @default.
• W2235596102 cites W2164125694 @default.
• W2235596102 cites W2164799855 @default.
• W2235596102 cites W2166673821 @default.
• W2235596102 cites W2167318859 @default.
• W2235596102 cites W2169453316 @default.
• W2235596102 cites W2171155970 @default.
• W2235596102 cites W2316702797 @default.
• W2235596102 cites W265458114 @default.
• W2235596102 cites W4229510242 @default.
• W2235596102 cites W4231460886 @default.
• W2235596102 cites W4236055423 @default.
• W2235596102 cites W4238935513 @default.
• W2235596102 cites W4250187127 @default.
• W2235596102 cites W4253391147 @default.
• W2235596102 cites W4298050013 @default.
• W2235596102 doi "https://doi.org/10.1007/s00284-015-0975-7" @default.
• W2235596102 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4828481" @default.
• W2235596102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26758707" @default.
• W2235596102 hasPublicationYear "2016" @default.
• W2235596102 type Work @default.
• W2235596102 sameAs 2235596102 @default.
• W2235596102 citedByCount "16" @default.
• W2235596102 countsByYear W22355961022016 @default.
• W2235596102 countsByYear W22355961022017 @default.

• next