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- W2235702988 abstract "<b>Objective</b> To evaluate the presence of placental α-microglobulin-1 (PAMG-1) in vaginal secretions in women with symptoms of preterm labor and assess its use as a predictor of preterm birth. <b>Study Design</b> A prospective cohort study of women between 16 and 34 weeks of gestation with symptoms of preterm labor and intact membranes was conducted. The presence of PAMG-1 was determined using a commercially available kit (AmniSure, AmniSure International LLC, Boston, MA). <b>Results</b> A total of 100 women were enrolled, of which 86 had outcome data available. PAMG-1 was detected in 19/86 (22.1%) subjects. These women were more likely to deliver within 7 days than those without PAMG-1 detected (6/19 [31.6%] vs. 5/67 [7.5%]; odds ratio 5.6; 95% confidence interval 1.5–21.6). These findings persisted after adjusting for potential confounders. The sensitivity was 54.6%, specificity was 82.7%, positive predictive value was 31.6%, and the negative predictive was 92.5%. <b>Conclusion</b> The presence of PAMG-1 is associated with an increased likelihood of delivery within 7 days." @default.
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- W2235702988 date "2015-09-14" @default.
- W2235702988 modified "2023-09-23" @default.
- W2235702988 title "Placental α-Microglobulin-1 in Vaginal Secretions of Women with Evidence of Preterm Labor" @default.
- W2235702988 doi "https://doi.org/10.1055/s-0035-1563710" @default.
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