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- W2235720177 abstract "For a number of years, researchers have noted that cancer cells have higher levels of ornithine decarboxylase (ODC) activity than do the corresponding noncancerous tissues (1-5). Because increases in ODC activity (and subsequently, the polyamines) occur regularly in the cell cycle and are necessary before successful cell division can occur, the exact role of these increased polyamine levels in tumorigenesis was not completely understood. It was unclear whether the increases in ODC and polyamine levels directly participated in the generation on the cancer phenotype, or whether these increases were only a result of the increased cell cycling that is a hallmark of many cancerous cells and tumors (1-4)." @default.
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- W2235720177 date "2006-01-01" @default.
- W2235720177 modified "2023-09-26" @default.
- W2235720177 title "Acute Increases in Intracellular Putrescine Lead to the Increase in Steady-State Levels of c-fos, c-jun, RING3, and Id-1 mRNAs" @default.
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- W2235720177 doi "https://doi.org/10.1007/978-1-59745-145-1_2" @default.
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