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• W2235727964 abstract "8 TIIVISTELMA (FINNISH SUMMARY) 9 REVIEW OF THE LITERATURE 10 1 TGF-Β & BMP SIGNALLING 10 1.1 The TGF-β superfamily 10 1.2 Formation and activation of TGF-β 10 1.3 The expression and bioavailability of BMP 11 1.4 Receptors in TGF-β and BMP signalling 12 1.5 Smad protein classification 12 1.6 Function of Smads 14 1.7 Non-Smad signalling pathways 14 1.8 Transcription factors 15 1.8.1 GATA-6 16 1.9 TGF-β family in development and disease 17 2 IDIOPATHIC PULMONARY FIBROSIS (IPF) 19 2.1 IPF and other interstitial lung diseases 19 2.2 Clinical features and diagnosis of IPF 19 2.3 Incidence and prevalence of IPF 19 2.4 Characteristic features of IPF 20 2.4.1 Usual interstitial pneumonia pattern 20 2.4.2 Epithelial-to-mesenchymal transition 20 2.4.3 Myofibroblasts 21 2.4.4 Extracellular matrix 21 2.4.5 Signalling molecules 22 2.5 Treatment options for IPF 23 3 EMPHYSEMA 26 3.1 Combined pulmonary fibrosis and emphysema 26 PRESENT STUDY 27 4 AIMS OF THE STUDY 27 5 MATERIALS & METHODS 28 5.1 Patient material 28 5.2 Cell lines 29" @default.
• W2235727964 created "2016-06-24" @default.
• W2235727964 creator A5017773605 @default.
• W2235727964 date "2012-10-26" @default.
• W2235727964 modified "2023-09-27" @default.
• W2235727964 title "Studies on TGF-β family signalling in the diseased lung tissue" @default.
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