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- W2236280261 abstract "Recently new reports have proved the pluripotency o f spermatogonial stem cells (SSCs) derived from male gonad. This pluripotent st em cells resembled Embryonic stem cells recognized as Embryonic Stem like cells (ES like cells). ES like cells forms sharp edge colonies that are immun opositive to pluripotency markers and have differentiation capacity to Ectode rmal, Mesodermal and Endodermal layers. ES like cells may have therapeut ique application in tissue engineering and treatment for disease because of th eir ability to differentiation into various cell types. Embryonic stem like cells deriv ed culturing of spermatogonial cells which has self-renewal and differentiation ca pacity to all three germ layers make them as a new and unlimited source for cell th erapy strategies. The perspective of pluripotency and differantiaion ability of ES like cells obtained in mice has clinical application in other species p articularly in humans that solves many problems of cell therapy in regenerative medicine. These characteristics propose the therapeutic use o f spermatogonial stem cells as a possible alternative source for generation of vario us cell types that are usful in treatment of degenerative diseases." @default.
- W2236280261 created "2016-06-24" @default.
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- W2236280261 date "2015-02-10" @default.
- W2236280261 modified "2023-09-25" @default.
- W2236280261 title "Spermatogonia stem cells: A new pluripotent source for repairment in regenerative medicine" @default.
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- W2236280261 doi "https://doi.org/10.7508/rmm.2015.01.001" @default.
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