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- W2236630874 abstract "Mice were injected intravenously with multilamellar liposomes containing hydrophilic muramyl dipeptide (MDP) or a lipophilic derivative of MDP, muramyl tripeptide (MTP-PE) which was inserted directly into the liposome bilayer membranes. Liposomes containing MTP-PE were superior to liposomes containing MDP for achieving high levels of prolonged activation of macrophages in the lungs. Moreover, multiple systemic injections of liposomes containing MTP-PE were more effective in the eradication of spontaneous lung and lymph node metastases than liposomes containing MDP. The data suggest that, when used in addition to conventional therapy, the systemic activation of macrophages with liposome-entrapped MTP-PE could be beneficial for the treatment of cancer metastases." @default.
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- W2236630874 date "1983-01-01" @default.
- W2236630874 modified "2023-09-26" @default.
- W2236630874 title "Systemic Activation of Macrophages and Treatment of Cancer Metastases by Liposomes containing Hydrophilic or Lipophilic Muramyl Dipeptide" @default.
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- W2236630874 doi "https://doi.org/10.1016/b978-0-08-029775-0.50035-3" @default.
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