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- W2236709746 abstract "The bilaterally symmetrical development of the frog larva is affected in a definite way by experimental hyperthyroidism. Normally in tadpole metamorphosis the left forelimb erupts first in about 70 per cent. of cases. With thyroid-accelerated metamorphosis of half-grown tadpoles practically 100 per cent. will put out the left forelimb first. Of 133 thyroid-treated animals of this kind every one protruded the left forelimb first. In the case of full-grown tadpoles already near the time of forelimb eruption, thyroid treatment may be followed during the first two days by some prior right forelimb eruptions; thereafter prior left forelimb eruption obtains. In other words, an original bias of an animal toward prior right forelimb eruption may not be changed by thyroid administration within two days.This effect of the thyroid on symmetrical development is explicable in terms of the original asymmetrical pattern of the respiratory apparatus (i. e., sinistrally located spiracle) coupled with the close anatomical relation of the forelimb to this apparatus.Thymus treatment brings about a larger percentage of prior right forelimb eruptions, thus reducing somewhat the normal majority in favor of prior left forelimb eruption." @default.
- W2236709746 created "2016-06-24" @default.
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- W2236709746 date "1925-05-01" @default.
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- W2236709746 title "ENDOCRINE GLANDS AND BILATERAL SYMMETRY: OBSERVATIONS UPON FORELIMB ERUPTION IN FROG LARVÆ UNDER TREATMENT WITH THYROID AND THYMUS EXTRACTS" @default.
- W2236709746 doi "https://doi.org/10.2307/1536601" @default.
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