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• W2236818970 abstract "The plant pathogen Agrobacterium tumefaciens carries a virulence gene system that is required for the initiation of crown gall tumors on susceptible plants. Expression of the vir genes is activated by the VirA/VirG two component regulatory system. VirA is a histidine kinase which signals the presence of certain chemicals found at the site of a plant wound. The receiver domain located at its carboxyl terminus defines VirA as a hybrid histidine kinase. Here, we show that the VirA receiver can interacts with the DNA-binding domain of VirG. This finding supports the hypothesis that the receiver acts as a recruiting factor for VirG. In addition, we show that removal of the VirA receiver allowed vir gene expression in response to glucose in a dose dependent manner, indicating that the receiver controls VirG activation and suggesting that the supplementary ChvE-sugar signal increases this activity." @default.
• W2236818970 created "2016-06-24" @default.
• W2236818970 creator A5041207516 @default.
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• W2236818970 date "2016-01-08" @default.
• W2236818970 modified "2023-09-25" @default.
• W2236818970 title "The Receiver of the Agrobacterium tumefaciens VirA Histidine Kinase Forms a Stable Interaction with VirG to Activate Virulence Gene Expression" @default.
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• W2236818970 doi "https://doi.org/10.3389/fmicb.2015.01546" @default.
• W2236818970 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4705274" @default.
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