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- W2237091872 abstract "Several arenavirus pathogens, such as Lassa and Junin viruses, inhibit macrophage activation, the molecular mechanism of which is unclear. We show that lymphocytic choriomeningitis virus (LCMV) can also inhibit macrophage activation, in contrast to Pichinde and Tacaribe viruses, which are not known to naturally cause human diseases. Using a recombinant Pichinde virus system, we show that the LCMV Z N-terminal domain (NTD) mediates the inhibition of macrophage activation and immune functions." @default.
- W2237091872 created "2016-06-24" @default.
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- W2237091872 date "2015-12-15" @default.
- W2237091872 modified "2023-10-14" @default.
- W2237091872 title "Differential Inhibition of Macrophage Activation by Lymphocytic Choriomeningitis Virus and Pichinde Virus Is Mediated by the Z Protein N-Terminal Domain" @default.
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- W2237091872 doi "https://doi.org/10.1128/jvi.01674-15" @default.
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