Matches in SemOpenAlex for { <https://semopenalex.org/work/W2237166997> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2237166997 abstract "OBJECTIVES: To assess the profile as well as the absolute number and percentage of true NK cells (CD56+CD16+CD3-), and NK and NKT cells (CD56+) in the peripheral blood of a cohort of patients with rheumatoid arthritis (RA) before and during rituximab (RTX) therapy. METHODS: Ten control patients (blood donors) and ten patients with RA were assessed. The latter group received two intravenous infusions of 1g RTX, separated by a 14 day interval. Immunophenotypic analyses of NK cells were conducted before and after infusion, or until clinical relapse. After six months, respondents and nonrespondents were reassessed according to American Rheumatology Criteria (ARC). RESULTS: The number of true NK cells did not significantly change after treatment with RTX. However, an increase in the percentage of CD56+ cells was observed between the first and second month after RTX infusion. Respondents also displayed a tendency toward an increased number of true NK cells after two months of treatment. At baseline, the number of NK cells was also found to be significantly higher in patients with RA than in control individuals (p<0.05). CONCLUSIONS: Respondents displayed a tendency toward an increase in the absolute number of true NK cells in the second month after RTX infusion. No significant changes in the profile and frequency of NK cells were found between preand post-RTX treatment assessments of patients with RA. However, it was found that patients with RA have a higher number of NK cells than control partcipants, suggesting a possible role of these cells in RA." @default.
- W2237166997 created "2016-06-24" @default.
- W2237166997 creator A5065118655 @default.
- W2237166997 date "2013-01-01" @default.
- W2237166997 modified "2023-09-27" @default.
- W2237166997 title "Células natural killer em uma coorte de pacientes com artrite reumatóide tratados com rituximabe" @default.
- W2237166997 cites W1912604628 @default.
- W2237166997 cites W1950776221 @default.
- W2237166997 cites W1970264918 @default.
- W2237166997 cites W1970422368 @default.
- W2237166997 cites W1972178991 @default.
- W2237166997 cites W1974820114 @default.
- W2237166997 cites W1977778943 @default.
- W2237166997 cites W1993689466 @default.
- W2237166997 cites W1997417141 @default.
- W2237166997 cites W1998618256 @default.
- W2237166997 cites W2008367158 @default.
- W2237166997 cites W2013716230 @default.
- W2237166997 cites W2020617435 @default.
- W2237166997 cites W2032771606 @default.
- W2237166997 cites W2033296826 @default.
- W2237166997 cites W2035298438 @default.
- W2237166997 cites W2063470653 @default.
- W2237166997 cites W2068928414 @default.
- W2237166997 cites W2077561088 @default.
- W2237166997 cites W2081734937 @default.
- W2237166997 cites W2110949372 @default.
- W2237166997 cites W2135668465 @default.
- W2237166997 cites W2138381780 @default.
- W2237166997 cites W2145076333 @default.
- W2237166997 cites W2152348310 @default.
- W2237166997 cites W2159106700 @default.
- W2237166997 cites W2160520392 @default.
- W2237166997 cites W2314331148 @default.
- W2237166997 cites W2410341557 @default.
- W2237166997 cites W2616655742 @default.
- W2237166997 hasPublicationYear "2013" @default.
- W2237166997 type Work @default.
- W2237166997 sameAs 2237166997 @default.
- W2237166997 citedByCount "0" @default.
- W2237166997 crossrefType "dissertation" @default.
- W2237166997 hasAuthorship W2237166997A5065118655 @default.
- W2237166997 hasConcept C114684123 @default.
- W2237166997 hasConcept C126322002 @default.
- W2237166997 hasConcept C167672396 @default.
- W2237166997 hasConcept C196166836 @default.
- W2237166997 hasConcept C203014093 @default.
- W2237166997 hasConcept C2777575956 @default.
- W2237166997 hasConcept C2781462264 @default.
- W2237166997 hasConcept C553184892 @default.
- W2237166997 hasConcept C71924100 @default.
- W2237166997 hasConcept C72563966 @default.
- W2237166997 hasConcept C8891405 @default.
- W2237166997 hasConcept C90924648 @default.
- W2237166997 hasConceptScore W2237166997C114684123 @default.
- W2237166997 hasConceptScore W2237166997C126322002 @default.
- W2237166997 hasConceptScore W2237166997C167672396 @default.
- W2237166997 hasConceptScore W2237166997C196166836 @default.
- W2237166997 hasConceptScore W2237166997C203014093 @default.
- W2237166997 hasConceptScore W2237166997C2777575956 @default.
- W2237166997 hasConceptScore W2237166997C2781462264 @default.
- W2237166997 hasConceptScore W2237166997C553184892 @default.
- W2237166997 hasConceptScore W2237166997C71924100 @default.
- W2237166997 hasConceptScore W2237166997C72563966 @default.
- W2237166997 hasConceptScore W2237166997C8891405 @default.
- W2237166997 hasConceptScore W2237166997C90924648 @default.
- W2237166997 hasLocation W22371669971 @default.
- W2237166997 hasOpenAccess W2237166997 @default.
- W2237166997 hasPrimaryLocation W22371669971 @default.
- W2237166997 isParatext "false" @default.
- W2237166997 isRetracted "false" @default.
- W2237166997 magId "2237166997" @default.
- W2237166997 workType "dissertation" @default.