FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2237345832> ?p ?o ?g. }

• W2237345832 endingPage "E706" @default.
• W2237345832 startingPage "E695" @default.
• W2237345832 abstract "To prevent the blood-borne interference and reflex actions via neighboring organs and the central nervous system, the study was conducted in an in vitro isolated stomach-gastric vagus nerve preparation obtained from overnight-fasted, urethan-anesthetized rats. Afferent unit action potentials were recorded from the gastric branch of the vagus nerve. The left gastric artery was catheterized for intra-arterial injection. In vitro we found that 1) 55/70 gastric vagal afferents (GVAs) were polymodal, responding to CCK-8 and mechanical stimuli, 13 were mechanoreceptive, and 2 were CCK-responsive; 2) sequential or randomized intra-arterial injections of CCK-8 (0.1-200 pmol) dose-dependently increased firing rate and reached the peak rate at 100 pmol; 3) the action was suppressed by CCK-A (Devazepide) but not by CCK-B (L-365,260) receptor antagonist; 4) neither antagonist blocked the mechanosensitivity of GVA fibers. These results are consistent with corresponding in vivo well-documented findings. Histological data indicate that the layered structure of the stomach wall was preserved in vitro for 6-8 h. Based on these results, it seems reasonable to use the in vitro preparation for conducting a study that is usually difficult to be performed in vivo. For instance, because there was no blood supply in vitro, the composition of the interstitial fluid, i.e., the ambient nerve terminals, can be better controlled and influenced by intra-arterial injection of a defined solution. Here we report that acutely changing the ambient CCK level by a conditioning stimulus (a preceding intra-arterial injection of increasing doses of CCK-8) reduced the CCK sensitivity of GVA terminals to a subsequent test stimulus (a constant dose of CCK-8 intra-arterial injection)." @default.
• W2237345832 created "2016-06-24" @default.
• W2237345832 creator A5055340952 @default.
• W2237345832 creator A5084136559 @default.
• W2237345832 date "2000-09-01" @default.
• W2237345832 modified "2023-10-01" @default.
• W2237345832 title "Effect of CCK pretreatment on the CCK sensitivity of rat polymodal gastric vagal afferent in vitro" @default.
• W2237345832 cites W1921911072 @default.
• W2237345832 cites W1964145632 @default.
• W2237345832 cites W1964803256 @default.
• W2237345832 cites W1965486601 @default.
• W2237345832 cites W1966989999 @default.
• W2237345832 cites W1968666385 @default.
• W2237345832 cites W1973668437 @default.
• W2237345832 cites W1978239142 @default.
• W2237345832 cites W1979438265 @default.
• W2237345832 cites W1989522186 @default.
• W2237345832 cites W1999763069 @default.
• W2237345832 cites W2009855715 @default.
• W2237345832 cites W2011625646 @default.
• W2237345832 cites W2026734427 @default.
• W2237345832 cites W2026981844 @default.
• W2237345832 cites W2030916992 @default.
• W2237345832 cites W2036707682 @default.
• W2237345832 cites W2050280286 @default.
• W2237345832 cites W2059067935 @default.
• W2237345832 cites W2077335083 @default.
• W2237345832 cites W2085768687 @default.
• W2237345832 cites W2089155821 @default.
• W2237345832 cites W2093053031 @default.
• W2237345832 cites W2124185943 @default.
• W2237345832 cites W2153111625 @default.
• W2237345832 cites W2168326668 @default.
• W2237345832 cites W2180503927 @default.
• W2237345832 cites W2183739350 @default.
• W2237345832 cites W2232115551 @default.
• W2237345832 cites W2235203115 @default.
• W2237345832 cites W2287184569 @default.
• W2237345832 cites W2290579942 @default.
• W2237345832 cites W2416533498 @default.
• W2237345832 cites W2423146595 @default.
• W2237345832 cites W301511349 @default.
• W2237345832 doi "https://doi.org/10.1152/ajpendo.2000.279.3.e695" @default.
• W2237345832 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10950839" @default.
• W2237345832 hasPublicationYear "2000" @default.
• W2237345832 type Work @default.
• W2237345832 sameAs 2237345832 @default.
• W2237345832 citedByCount "19" @default.
• W2237345832 countsByYear W22373458322013 @default.
• W2237345832 countsByYear W22373458322015 @default.
• W2237345832 countsByYear W22373458322016 @default.
• W2237345832 crossrefType "journal-article" @default.
• W2237345832 hasAuthorship W2237345832A5055340952 @default.
• W2237345832 hasAuthorship W2237345832A5084136559 @default.
• W2237345832 hasConcept C115504290 @default.
• W2237345832 hasConcept C126322002 @default.
• W2237345832 hasConcept C134018914 @default.
• W2237345832 hasConcept C150903083 @default.
• W2237345832 hasConcept C170493617 @default.
• W2237345832 hasConcept C185592680 @default.
• W2237345832 hasConcept C202751555 @default.
• W2237345832 hasConcept C207001950 @default.
• W2237345832 hasConcept C24998067 @default.
• W2237345832 hasConcept C2776885963 @default.
• W2237345832 hasConcept C2778720886 @default.
• W2237345832 hasConcept C2779422922 @default.
• W2237345832 hasConcept C2781404750 @default.
• W2237345832 hasConcept C42219234 @default.
• W2237345832 hasConcept C55493867 @default.
• W2237345832 hasConcept C71924100 @default.
• W2237345832 hasConcept C83974742 @default.
• W2237345832 hasConcept C86803240 @default.
• W2237345832 hasConceptScore W2237345832C115504290 @default.
• W2237345832 hasConceptScore W2237345832C126322002 @default.
• W2237345832 hasConceptScore W2237345832C134018914 @default.
• W2237345832 hasConceptScore W2237345832C150903083 @default.
• W2237345832 hasConceptScore W2237345832C170493617 @default.
• W2237345832 hasConceptScore W2237345832C185592680 @default.
• W2237345832 hasConceptScore W2237345832C202751555 @default.
• W2237345832 hasConceptScore W2237345832C207001950 @default.
• W2237345832 hasConceptScore W2237345832C24998067 @default.
• W2237345832 hasConceptScore W2237345832C2776885963 @default.
• W2237345832 hasConceptScore W2237345832C2778720886 @default.
• W2237345832 hasConceptScore W2237345832C2779422922 @default.
• W2237345832 hasConceptScore W2237345832C2781404750 @default.
• W2237345832 hasConceptScore W2237345832C42219234 @default.
• W2237345832 hasConceptScore W2237345832C55493867 @default.
• W2237345832 hasConceptScore W2237345832C71924100 @default.
• W2237345832 hasConceptScore W2237345832C83974742 @default.
• W2237345832 hasConceptScore W2237345832C86803240 @default.
• W2237345832 hasIssue "3" @default.
• W2237345832 hasLocation W22373458321 @default.
• W2237345832 hasLocation W22373458322 @default.
• W2237345832 hasOpenAccess W2237345832 @default.
• W2237345832 hasPrimaryLocation W22373458321 @default.
• W2237345832 hasRelatedWork W1789692432 @default.
• W2237345832 hasRelatedWork W1974471078 @default.
• W2237345832 hasRelatedWork W1983217027 @default.

• next