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• W2237635982 abstract "The analysis of elemental impurities in pharmaceuticals has traditionally been performed using plasma-based instrumental techniques, such as inductively coupled plasma-optical emission spectroscopy or inductively coupled plasma-mass spectrometry, due to their inherent sensitivity, selectivity, and precision; however, during development activities, there are a variety of sample types that do not require the sensitivity that these expensive and time-consuming techniques provide. Pharmaceutical process chemists often need a rapid and relative determination of the elemental content to direct them in optimizing the effectiveness or efficiency of their synthetic process. This article will provide the application of a field-portable X-ray fluorescence instrument as a hands-on screening tool for chemists to determine the effectiveness of metal catalyst scavenger studies. Three case studies will be provided to illustrate the usefulness of the technique." @default.
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• W2237635982 date "2015-12-03" @default.
• W2237635982 modified "2023-10-17" @default.
• W2237635982 title "Use of a Field-Portable XRF Instrument To Facilitate Metal Catalyst Scavenger Screening" @default.
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• W2237635982 doi "https://doi.org/10.1021/acs.oprd.5b00300" @default.
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