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• W2238008538 endingPage "443" @default.
• W2238008538 startingPage "431" @default.
• W2238008538 abstract "Despite successful restoration of epicardial coronary blood flow, a significant proportion of patients with ST-elevation myocardial infarction suffer from an impairment of the microvascular perfusion – a phenomenon termed no-reflow or microvascular injury (MVI). The underlying pathophysiology is complex and likely multifactorial. It is well established that MVI is associated with worse clinical outcome. Although MVI can be detected during coronary intervention and the post-infarction period, its prevention and treatment strategies remain a major challenge since most results of clinical studies have been disappointing so far. This review provides an overview on the main pathophysiological mechanisms of MVI and its diagnostic approaches. Moreover, it will discuss its clinical consequences and current strategies of prevention and treatment." @default.
• W2238008538 created "2016-06-24" @default.
• W2238008538 creator A5034833267 @default.
• W2238008538 creator A5038605040 @default.
• W2238008538 creator A5040412372 @default.
• W2238008538 creator A5042017136 @default.
• W2238008538 creator A5042630628 @default.
• W2238008538 creator A5062171901 @default.
• W2238008538 creator A5070736175 @default.
• W2238008538 creator A5087395048 @default.
• W2238008538 date "2016-01-22" @default.
• W2238008538 modified "2023-09-23" @default.
• W2238008538 title "The challenges and impact of microvascular injury in ST-elevation myocardial infarction" @default.
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