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- W2238222761 abstract "PurposeDeficiency of interleukin-1 receptor antagonist (DIRA) is a rare life-threatening autoinflammatory disease caused by autosomal recessive mutations in IL1RN. DIRA presents clinically with early onset generalized pustulosis, multifocal osteomyelitis, and elevation of acute phase reactants. We evaluated and treated an antibiotic-unresponsive patient with presumed DIRA with recombinant IL-1Ra (anakinra). The patient developed anaphylaxis to anakinra and was subsequently desensitized." @default.
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- W2238222761 date "2015-09-28" @default.
- W2238222761 modified "2023-09-24" @default.
- W2238222761 title "Deficiency of Interleukin-1 Receptor Antagonist (DIRA): Report of the First Indian Patient and a Novel Deletion Affecting IL1RN" @default.
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- W2238222761 doi "https://doi.org/10.1186/1546-0096-13-s1-p143" @default.
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