Matches in SemOpenAlex for { <https://semopenalex.org/work/W2238316596> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2238316596 abstract "As-needed formoterol can effectively relieve asthma symptoms. Since budesonide/formoterol is available as maintenance and reliever therapy in Asia, formoterol is now being used as-needed, but always with concomitant inhaled corticosteroids. The objective of this analysis was to assess the safety and efficacy of formoterol therapy in patients in East Asia (China, Indonesia, Korea, the Philippines and Singapore) with asthma.Post-hoc analyses of data from the East Asian population of the RELIEF (REal LIfe EFfectiveness of Oxis® Turbuhaler® as-needed in asthmatic patients; study identification code: SD-037-0699) study were performed.This sub-group comprised 2834 randomised patients (formoterol n = 1418; salbutamol n = 1416) with mean age 35 years; 50.7% were male. 2678 patients completed the study. There was no significant difference in the total number of adverse events (AEs) reported in the formoterol and salbutamol groups (21.3% vs 20.9% of patients; p = 0.813), nor in the total number of serious AEs and/or discontinuations due to AEs (4.6% vs 5.5%, respectively; p = 0.323). Compared with salbutamol, formoterol was associated with a significantly longer time to first exacerbation (hazard ratio 0.86; p = 0.023) and a 14% reduction in the risk of any exacerbation (p < 0.05). Relative to salbutamol, mean adjusted reliever medication use throughout the study was significantly lower in the formoterol group (p = 0.017) and the risk of increased asthma medication use was 20% lower with formoterol (p = 0.005).Among patients with asthma in East Asia, as-needed formoterol and salbutamol had similar safety profiles but, compared with salbutamol, formoterol reduced the risk of exacerbations, increased the time to first exacerbation and reduced the need for reliever medication." @default.
- W2238316596 created "2016-06-24" @default.
- W2238316596 creator A5004698472 @default.
- W2238316596 creator A5005691727 @default.
- W2238316596 creator A5006832289 @default.
- W2238316596 creator A5022112843 @default.
- W2238316596 creator A5045492083 @default.
- W2238316596 creator A5070296640 @default.
- W2238316596 creator A5070601875 @default.
- W2238316596 creator A5075691213 @default.
- W2238316596 creator A5083474599 @default.
- W2238316596 date "2016-01-12" @default.
- W2238316596 modified "2023-10-10" @default.
- W2238316596 title "Formoterol as reliever medication in asthma: a post-hoc analysis of the subgroup of the RELIEF study in East Asia" @default.
- W2238316596 cites W1598054520 @default.
- W2238316596 cites W2056770521 @default.
- W2238316596 cites W2107869915 @default.
- W2238316596 cites W2113552278 @default.
- W2238316596 cites W2139373697 @default.
- W2238316596 cites W2143869213 @default.
- W2238316596 cites W2144587984 @default.
- W2238316596 cites W2148393792 @default.
- W2238316596 cites W49086682 @default.
- W2238316596 doi "https://doi.org/10.1186/s12890-015-0166-0" @default.
- W2238316596 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4711052" @default.
- W2238316596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26758377" @default.
- W2238316596 hasPublicationYear "2016" @default.
- W2238316596 type Work @default.
- W2238316596 sameAs 2238316596 @default.
- W2238316596 citedByCount "2" @default.
- W2238316596 countsByYear W22383165962022 @default.
- W2238316596 countsByYear W22383165962023 @default.
- W2238316596 crossrefType "journal-article" @default.
- W2238316596 hasAuthorship W2238316596A5004698472 @default.
- W2238316596 hasAuthorship W2238316596A5005691727 @default.
- W2238316596 hasAuthorship W2238316596A5006832289 @default.
- W2238316596 hasAuthorship W2238316596A5022112843 @default.
- W2238316596 hasAuthorship W2238316596A5045492083 @default.
- W2238316596 hasAuthorship W2238316596A5070296640 @default.
- W2238316596 hasAuthorship W2238316596A5070601875 @default.
- W2238316596 hasAuthorship W2238316596A5075691213 @default.
- W2238316596 hasAuthorship W2238316596A5083474599 @default.
- W2238316596 hasBestOaLocation W22383165961 @default.
- W2238316596 hasConcept C126322002 @default.
- W2238316596 hasConcept C197934379 @default.
- W2238316596 hasConcept C2776042228 @default.
- W2238316596 hasConcept C2776136866 @default.
- W2238316596 hasConcept C2777014857 @default.
- W2238316596 hasConcept C2777394947 @default.
- W2238316596 hasConcept C2779871671 @default.
- W2238316596 hasConcept C2908647359 @default.
- W2238316596 hasConcept C2909086917 @default.
- W2238316596 hasConcept C42219234 @default.
- W2238316596 hasConcept C67761136 @default.
- W2238316596 hasConcept C71924100 @default.
- W2238316596 hasConcept C99454951 @default.
- W2238316596 hasConceptScore W2238316596C126322002 @default.
- W2238316596 hasConceptScore W2238316596C197934379 @default.
- W2238316596 hasConceptScore W2238316596C2776042228 @default.
- W2238316596 hasConceptScore W2238316596C2776136866 @default.
- W2238316596 hasConceptScore W2238316596C2777014857 @default.
- W2238316596 hasConceptScore W2238316596C2777394947 @default.
- W2238316596 hasConceptScore W2238316596C2779871671 @default.
- W2238316596 hasConceptScore W2238316596C2908647359 @default.
- W2238316596 hasConceptScore W2238316596C2909086917 @default.
- W2238316596 hasConceptScore W2238316596C42219234 @default.
- W2238316596 hasConceptScore W2238316596C67761136 @default.
- W2238316596 hasConceptScore W2238316596C71924100 @default.
- W2238316596 hasConceptScore W2238316596C99454951 @default.
- W2238316596 hasIssue "1" @default.
- W2238316596 hasLocation W22383165961 @default.
- W2238316596 hasLocation W22383165962 @default.
- W2238316596 hasLocation W22383165963 @default.
- W2238316596 hasLocation W22383165964 @default.
- W2238316596 hasOpenAccess W2238316596 @default.
- W2238316596 hasPrimaryLocation W22383165961 @default.
- W2238316596 hasRelatedWork W1701559121 @default.
- W2238316596 hasRelatedWork W1904732989 @default.
- W2238316596 hasRelatedWork W1973764452 @default.
- W2238316596 hasRelatedWork W2052945963 @default.
- W2238316596 hasRelatedWork W2157910210 @default.
- W2238316596 hasRelatedWork W2385963534 @default.
- W2238316596 hasRelatedWork W2783705291 @default.
- W2238316596 hasRelatedWork W2902003192 @default.
- W2238316596 hasRelatedWork W3121769058 @default.
- W2238316596 hasRelatedWork W4223896114 @default.
- W2238316596 hasVolume "16" @default.
- W2238316596 isParatext "false" @default.
- W2238316596 isRetracted "false" @default.
- W2238316596 magId "2238316596" @default.
- W2238316596 workType "article" @default.