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- W2238422740 abstract "Acacia podalyriifolia A. Cunn. ex G. Don, Leguminosae-Mimosoideae, is an exotic species, widely distributed in southern Brazil. Phytochemical evaluations performed showed the presence of flavonoids, tanines, phenolic compounds and steroids/terpenoids in the flowers, while the material obtained from the leaves were ascertained alkaloids, coumarins, flavonoids, tanines, phenolic compounds, quinones, and steroids/terpenoids. In determining the content of phenolic compounds using the Folin Ciocalteu reagent, the ethyl acetate fractions from the flowers and the leaves had presented the greatest content of phenolic compounds. The hexane, dichloromethane and ethyl acetate fractions and the residue which precipitated in the obtaining of ethanol extracts from the flowers and leaves were submitted to chromatographic methods for the isolation of substances. As isolated and identified phenolic major compounds from the flowers and the leaves were obtained the flavanones 5-D-glicosil-naringenine and naringenine, and the β-diketone denominated 16, 18 tritriacontanedione. The analysis of antibacterial activity, carried out by bioautography, disk diffusion and minimum inhibitory concentration proved that the ethyl acetate fraction obtained from both the leaves and flowers, is the most active, inhibiting gram positive and gram negative bacterial strains, in degrees variable depending on the strain used. For the isolated compounds, in the evaluated concentrations, only naringenin has demonstrated antibacterial action. For the antioxidant activity, performed by the methodologies which employ the free radical 2,2-diphenyl-1picrylhydrazyl (DPPH), phosphomolybdenum complex formation and TBARS test, it should be specially noted that it also showed the ethyl acetate fraction, demonstrating to be even more active than the standards used, depending on which technique was used. The isolated flavanones demonstrated antioxidant activity, although lower than the played by the original fractions; for the 16, 18 tritriacontanedione, this activity was very slight. In the evaluation of general toxicity using the Artemia salina, the dichloromethane fraction obtained from the flowers proved to be the most cytotoxic in these assays. Regarding the allelopathic potential observed on the seeds of Lactuca sativa, variety “Baba”, against the samples obtained from flowers and leaves, although it has not affected the germination of seedlings, caused significant influences on the growth when compared to control. The isolated compounds presented significant effects on seedling growth, contributing to the allelopathic activity observed with their origin fractions." @default.
- W2238422740 created "2016-06-24" @default.
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- W2238422740 date "2011-03-10" @default.
- W2238422740 modified "2023-09-23" @default.
- W2238422740 title "Estudo químico e biológico das flores e das folhas de Acacia podalyriifolia A. Cunn. Ex G. Don, Leguminosae - Mimosoideae" @default.
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