Matches in SemOpenAlex for { <https://semopenalex.org/work/W2238534170> ?p ?o ?g. }
- W2238534170 abstract "The purpose of the study was the assessment of the expression of IL-1β and IL-6, and the proteins regulating their biological activity, namely IL-1RII, IL-1Ra, as well as sIL-6Rα, sgp-130 in leukemic lymphocytes and autologous neutrophils of B-CLL patients.The study involved a group of B-cell chronic lymphocytic leukemia patients and healthy volunteer blood donors. The presence of chosen proteins and their natural regulators was confirmed by Western blot.Western blot analysis showed a decreased expression of IL-1β and IL-6 in the leukocytes of B-CLL patients. Decreased expression of sIL-6Rα has been observed in lymphocytes, with a simultaneous increase of expression in PMNs. Lower expression of sgp-130 was found in B cells while its expression was elevated in the neutrophils of patients in early stages of the disease.The changes observed in the expression of IL-1 and IL-6 seem to exclude their immediate involvement in the progress of B-CLL. However, the presented changes in the expression of proteins regulating IL-1β and IL-6 in PMNs indicate a potential role of early immune response cells also in advanced stages of the disease." @default.
- W2238534170 created "2016-06-24" @default.
- W2238534170 creator A5008741055 @default.
- W2238534170 creator A5010593363 @default.
- W2238534170 creator A5018546674 @default.
- W2238534170 creator A5049723469 @default.
- W2238534170 creator A5051188316 @default.
- W2238534170 creator A5055272591 @default.
- W2238534170 creator A5061356652 @default.
- W2238534170 creator A5062932374 @default.
- W2238534170 creator A5068687255 @default.
- W2238534170 creator A5069752933 @default.
- W2238534170 date "2016-09-01" @default.
- W2238534170 modified "2023-09-24" @default.
- W2238534170 title "Expression of IL-1 and IL-6 and their natural regulators in leukocytes of B-cell chronic lymphocytic leukaemia patients" @default.
- W2238534170 cites W1511164593 @default.
- W2238534170 cites W1518549789 @default.
- W2238534170 cites W154103547 @default.
- W2238534170 cites W191193518 @default.
- W2238534170 cites W1966067386 @default.
- W2238534170 cites W1966370165 @default.
- W2238534170 cites W1968088810 @default.
- W2238534170 cites W1995837249 @default.
- W2238534170 cites W2001941062 @default.
- W2238534170 cites W2007000374 @default.
- W2238534170 cites W2018498519 @default.
- W2238534170 cites W2028194167 @default.
- W2238534170 cites W2034558622 @default.
- W2238534170 cites W2056772662 @default.
- W2238534170 cites W2059426702 @default.
- W2238534170 cites W2063751527 @default.
- W2238534170 cites W2075760937 @default.
- W2238534170 cites W2083467392 @default.
- W2238534170 cites W2085451664 @default.
- W2238534170 cites W2099054255 @default.
- W2238534170 cites W2101064494 @default.
- W2238534170 cites W2106250673 @default.
- W2238534170 cites W2111675032 @default.
- W2238534170 cites W2142099365 @default.
- W2238534170 cites W2145866317 @default.
- W2238534170 cites W2150107812 @default.
- W2238534170 cites W2166880009 @default.
- W2238534170 cites W2221262359 @default.
- W2238534170 cites W2323490326 @default.
- W2238534170 cites W2412225035 @default.
- W2238534170 cites W2413775432 @default.
- W2238534170 cites W2414176003 @default.
- W2238534170 cites W2417954091 @default.
- W2238534170 cites W2433806490 @default.
- W2238534170 cites W312077114 @default.
- W2238534170 cites W74141936 @default.
- W2238534170 doi "https://doi.org/10.1016/j.advms.2015.12.006" @default.
- W2238534170 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26876087" @default.
- W2238534170 hasPublicationYear "2016" @default.
- W2238534170 type Work @default.
- W2238534170 sameAs 2238534170 @default.
- W2238534170 citedByCount "4" @default.
- W2238534170 countsByYear W22385341702019 @default.
- W2238534170 countsByYear W22385341702020 @default.
- W2238534170 countsByYear W22385341702021 @default.
- W2238534170 crossrefType "journal-article" @default.
- W2238534170 hasAuthorship W2238534170A5008741055 @default.
- W2238534170 hasAuthorship W2238534170A5010593363 @default.
- W2238534170 hasAuthorship W2238534170A5018546674 @default.
- W2238534170 hasAuthorship W2238534170A5049723469 @default.
- W2238534170 hasAuthorship W2238534170A5051188316 @default.
- W2238534170 hasAuthorship W2238534170A5055272591 @default.
- W2238534170 hasAuthorship W2238534170A5061356652 @default.
- W2238534170 hasAuthorship W2238534170A5062932374 @default.
- W2238534170 hasAuthorship W2238534170A5068687255 @default.
- W2238534170 hasAuthorship W2238534170A5069752933 @default.
- W2238534170 hasConcept C104317684 @default.
- W2238534170 hasConcept C203014093 @default.
- W2238534170 hasConcept C2776415932 @default.
- W2238534170 hasConcept C2777938653 @default.
- W2238534170 hasConcept C2778461978 @default.
- W2238534170 hasConcept C55493867 @default.
- W2238534170 hasConcept C71924100 @default.
- W2238534170 hasConcept C86803240 @default.
- W2238534170 hasConcept C8891405 @default.
- W2238534170 hasConceptScore W2238534170C104317684 @default.
- W2238534170 hasConceptScore W2238534170C203014093 @default.
- W2238534170 hasConceptScore W2238534170C2776415932 @default.
- W2238534170 hasConceptScore W2238534170C2777938653 @default.
- W2238534170 hasConceptScore W2238534170C2778461978 @default.
- W2238534170 hasConceptScore W2238534170C55493867 @default.
- W2238534170 hasConceptScore W2238534170C71924100 @default.
- W2238534170 hasConceptScore W2238534170C86803240 @default.
- W2238534170 hasConceptScore W2238534170C8891405 @default.
- W2238534170 hasLocation W22385341701 @default.
- W2238534170 hasLocation W22385341702 @default.
- W2238534170 hasOpenAccess W2238534170 @default.
- W2238534170 hasPrimaryLocation W22385341701 @default.
- W2238534170 hasRelatedWork W1572020652 @default.
- W2238534170 hasRelatedWork W1911352726 @default.
- W2238534170 hasRelatedWork W1964313892 @default.
- W2238534170 hasRelatedWork W1979666223 @default.
- W2238534170 hasRelatedWork W1988580189 @default.
- W2238534170 hasRelatedWork W1991150532 @default.
- W2238534170 hasRelatedWork W1991285265 @default.