Matches in SemOpenAlex for { <https://semopenalex.org/work/W2238551811> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W2238551811 abstract "E. coli K-12 contains nine csp paralogs, cspA – cspI.Although the csp paralogs are conserved sequences that producehighly similar proteins, expression of each of these genes requiresa different means of induction. While cspA, cspB, cspG, and cspIare induced by cold shock, cspC and cspE are constitutivelyexpressed. cspD is induced by stationary phase. The type ofinduction, if any, needed for cspF and cspH is not known. Studiesof CspE have demonstrated that the overexpression of this proteincan confer a 10-fold resistance to the DNA decondensing agent,camphor, and upregulates the E. coli rcsA gene by 1.7-fold.Phenotypic assays to determine Csp function show that stablized Cspproteins that are normally degraded by Lon protease (CspC, CspE,CspG, CspI) display resistance to camphor and upregulate the rcsAgene when they are expressed from an arabinose inducible vectorharbored in a lon- strain. Csp proteins that are not stabilized(CspA, Csp B, CspF, and CspH), even in the lon- mutant strain, didnot display these phenotypes. Csp protein function was furtherassessed by studying the pattern of Csp protein accumulation acrossvarious phases of cell growth. When expression is controlled froman inducible promoter, CspA, CspG, and CspI stability in a lon-strain tends to peak during late log and stationary phase. CspC andCspE stability tends to remain the same throughout each of thegrowth phases observed, while CspB, CspF, and CspH are not presentat all. Overall, my work suggests that CspC, CspE, CspG, and CspIpossess similar functions, which they each perform under differentenvironmental conditions and at different phases of cellgrowth." @default.
- W2238551811 created "2016-06-24" @default.
- W2238551811 creator A5048010848 @default.
- W2238551811 date "2004-01-01" @default.
- W2238551811 modified "2023-09-26" @default.
- W2238551811 title "Functional Characterization of the csp Homologs of E. coli K-12" @default.
- W2238551811 hasPublicationYear "2004" @default.
- W2238551811 type Work @default.
- W2238551811 sameAs 2238551811 @default.
- W2238551811 citedByCount "0" @default.
- W2238551811 crossrefType "journal-article" @default.
- W2238551811 hasAuthorship W2238551811A5048010848 @default.
- W2238551811 hasConcept C104317684 @default.
- W2238551811 hasConcept C105702510 @default.
- W2238551811 hasConcept C127716648 @default.
- W2238551811 hasConcept C143065580 @default.
- W2238551811 hasConcept C153911025 @default.
- W2238551811 hasConcept C205260736 @default.
- W2238551811 hasConcept C2778022156 @default.
- W2238551811 hasConcept C55493867 @default.
- W2238551811 hasConcept C86803240 @default.
- W2238551811 hasConcept C95444343 @default.
- W2238551811 hasConceptScore W2238551811C104317684 @default.
- W2238551811 hasConceptScore W2238551811C105702510 @default.
- W2238551811 hasConceptScore W2238551811C127716648 @default.
- W2238551811 hasConceptScore W2238551811C143065580 @default.
- W2238551811 hasConceptScore W2238551811C153911025 @default.
- W2238551811 hasConceptScore W2238551811C205260736 @default.
- W2238551811 hasConceptScore W2238551811C2778022156 @default.
- W2238551811 hasConceptScore W2238551811C55493867 @default.
- W2238551811 hasConceptScore W2238551811C86803240 @default.
- W2238551811 hasConceptScore W2238551811C95444343 @default.
- W2238551811 hasLocation W22385518111 @default.
- W2238551811 hasOpenAccess W2238551811 @default.
- W2238551811 hasPrimaryLocation W22385518111 @default.
- W2238551811 hasRelatedWork W1481310511 @default.
- W2238551811 hasRelatedWork W1500152947 @default.
- W2238551811 hasRelatedWork W1539516473 @default.
- W2238551811 hasRelatedWork W176487628 @default.
- W2238551811 hasRelatedWork W1775318543 @default.
- W2238551811 hasRelatedWork W1901701829 @default.
- W2238551811 hasRelatedWork W1928071293 @default.
- W2238551811 hasRelatedWork W1982153864 @default.
- W2238551811 hasRelatedWork W2015095310 @default.
- W2238551811 hasRelatedWork W2051823604 @default.
- W2238551811 hasRelatedWork W2086484031 @default.
- W2238551811 hasRelatedWork W2092077402 @default.
- W2238551811 hasRelatedWork W2099200059 @default.
- W2238551811 hasRelatedWork W2103173221 @default.
- W2238551811 hasRelatedWork W2112311560 @default.
- W2238551811 hasRelatedWork W2117626016 @default.
- W2238551811 hasRelatedWork W2140863066 @default.
- W2238551811 hasRelatedWork W2171265386 @default.
- W2238551811 hasRelatedWork W2494786743 @default.
- W2238551811 hasRelatedWork W2745987724 @default.
- W2238551811 isParatext "false" @default.
- W2238551811 isRetracted "false" @default.
- W2238551811 magId "2238551811" @default.
- W2238551811 workType "article" @default.