FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2238644429> ?p ?o ?g. }

• W2238644429 endingPage "e0146594" @default.
• W2238644429 startingPage "e0146594" @default.
• W2238644429 abstract "Fish spawning is often used as an integrated measure of reproductive toxicity, and an indicator of aquatic ecosystem health in the context of forecasting potential population-level effects considered important for ecological risk assessment. Consequently, there is a need for flexible, widely-applicable, biologically-based models that can predict changes in fecundity in response to chemical exposures, based on readily measured biochemical endpoints, such as plasma vitellogenin (VTG) concentrations, as input parameters. Herein we describe a MATLAB® version of an oocyte growth dynamics model for fathead minnows (Pimephales promelas) with a graphical user interface based upon a previously published model developed with MCSim software and evaluated with data from fathead minnows exposed to an androgenic chemical, 17β-trenbolone. We extended the evaluation of our new model to include six chemicals that inhibit enzymes involved in steroid biosynthesis: fadrozole, ketoconazole, propiconazole, prochloraz, fenarimol, and trilostane. In addition, for unexposed fathead minnows from group spawning design studies, and those exposed to the six chemicals, we evaluated whether the model is capable of predicting the average number of eggs per spawn and the average number of spawns per female, which was not evaluated previously. The new model is significantly improved in terms of ease of use, platform independence, and utility for providing output in a format that can be used as input into a population dynamics model. Model-predicted minimum and maximum cumulative fecundity over time encompassed the observed data for fadrozole and most propiconazole, prochloraz, fenarimol and trilostane treatments, but did not consistently replicate results from ketoconazole treatments. For average fecundity (eggs•female(-1)•day(-1)), eggs per spawn, and the number of spawns per female, the range of model-predicted values generally encompassed the experimentally observed values. Overall, we found that the model predicts reproduction metrics robustly and its predictions capture the variability in the experimentally observed data." @default.
• W2238644429 created "2016-06-24" @default.
• W2238644429 creator A5006637894 @default.
• W2238644429 creator A5036474832 @default.
• W2238644429 creator A5038610645 @default.
• W2238644429 creator A5044171138 @default.
• W2238644429 creator A5045705423 @default.
• W2238644429 creator A5075371599 @default.
• W2238644429 date "2016-01-12" @default.
• W2238644429 modified "2023-10-11" @default.
• W2238644429 title "Predicting Fecundity of Fathead Minnows (Pimephales promelas) Exposed to Endocrine-Disrupting Chemicals Using a MATLAB®-Based Model of Oocyte Growth Dynamics" @default.
• W2238644429 cites W1968766422 @default.
• W2238644429 cites W1970197319 @default.
• W2238644429 cites W1987993545 @default.
• W2238644429 cites W1992096727 @default.
• W2238644429 cites W1996848250 @default.
• W2238644429 cites W2000089305 @default.
• W2238644429 cites W2000849916 @default.
• W2238644429 cites W2013053268 @default.
• W2238644429 cites W2014961652 @default.
• W2238644429 cites W2021562385 @default.
• W2238644429 cites W2021771737 @default.
• W2238644429 cites W2024957336 @default.
• W2238644429 cites W2027428699 @default.
• W2238644429 cites W2042161432 @default.
• W2238644429 cites W2059651883 @default.
• W2238644429 cites W2062557558 @default.
• W2238644429 cites W2068612915 @default.
• W2238644429 cites W2072942932 @default.
• W2238644429 cites W2093587873 @default.
• W2238644429 cites W2098239925 @default.
• W2238644429 cites W2126168000 @default.
• W2238644429 cites W2133100606 @default.
• W2238644429 cites W2139631347 @default.
• W2238644429 cites W2149008445 @default.
• W2238644429 cites W2152823264 @default.
• W2238644429 cites W2153992735 @default.
• W2238644429 cites W2156416555 @default.
• W2238644429 cites W2165494629 @default.
• W2238644429 cites W2166500798 @default.
• W2238644429 cites W2169412126 @default.
• W2238644429 cites W66075962 @default.
• W2238644429 doi "https://doi.org/10.1371/journal.pone.0146594" @default.
• W2238644429 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4710531" @default.
• W2238644429 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26756814" @default.
• W2238644429 hasPublicationYear "2016" @default.
• W2238644429 type Work @default.
• W2238644429 sameAs 2238644429 @default.
• W2238644429 citedByCount "13" @default.
• W2238644429 countsByYear W22386444292016 @default.
• W2238644429 countsByYear W22386444292017 @default.
• W2238644429 countsByYear W22386444292018 @default.
• W2238644429 countsByYear W22386444292019 @default.
• W2238644429 countsByYear W22386444292021 @default.
• W2238644429 countsByYear W22386444292022 @default.
• W2238644429 crossrefType "journal-article" @default.
• W2238644429 hasAuthorship W2238644429A5006637894 @default.
• W2238644429 hasAuthorship W2238644429A5036474832 @default.
• W2238644429 hasAuthorship W2238644429A5038610645 @default.
• W2238644429 hasAuthorship W2238644429A5044171138 @default.
• W2238644429 hasAuthorship W2238644429A5045705423 @default.
• W2238644429 hasAuthorship W2238644429A5075371599 @default.
• W2238644429 hasBestOaLocation W22386444291 @default.
• W2238644429 hasConcept C115346097 @default.
• W2238644429 hasConcept C2776451064 @default.
• W2238644429 hasConcept C2779078696 @default.
• W2238644429 hasConcept C2908647359 @default.
• W2238644429 hasConcept C2909208804 @default.
• W2238644429 hasConcept C2993305272 @default.
• W2238644429 hasConcept C33070731 @default.
• W2238644429 hasConcept C505870484 @default.
• W2238644429 hasConcept C67283656 @default.
• W2238644429 hasConcept C71924100 @default.
• W2238644429 hasConcept C86803240 @default.
• W2238644429 hasConcept C99454951 @default.
• W2238644429 hasConceptScore W2238644429C115346097 @default.
• W2238644429 hasConceptScore W2238644429C2776451064 @default.
• W2238644429 hasConceptScore W2238644429C2779078696 @default.
• W2238644429 hasConceptScore W2238644429C2908647359 @default.
• W2238644429 hasConceptScore W2238644429C2909208804 @default.
• W2238644429 hasConceptScore W2238644429C2993305272 @default.
• W2238644429 hasConceptScore W2238644429C33070731 @default.
• W2238644429 hasConceptScore W2238644429C505870484 @default.
• W2238644429 hasConceptScore W2238644429C67283656 @default.
• W2238644429 hasConceptScore W2238644429C71924100 @default.
• W2238644429 hasConceptScore W2238644429C86803240 @default.
• W2238644429 hasConceptScore W2238644429C99454951 @default.
• W2238644429 hasIssue "1" @default.
• W2238644429 hasLocation W22386444291 @default.
• W2238644429 hasLocation W22386444292 @default.
• W2238644429 hasLocation W22386444293 @default.
• W2238644429 hasLocation W22386444294 @default.
• W2238644429 hasLocation W22386444295 @default.
• W2238644429 hasLocation W22386444296 @default.
• W2238644429 hasOpenAccess W2238644429 @default.
• W2238644429 hasPrimaryLocation W22386444291 @default.
• W2238644429 hasRelatedWork W1606777754 @default.
• W2238644429 hasRelatedWork W1779270707 @default.

• next