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- W2238685771 abstract "Publisher Summary Aminobutyric acid (ABA) is unevenly distributed in various areas of the nervous system. Endogenously formed γ-ABA in animals is virtually limited to nervous tissue. Significant amounts are found in certain bacteria and in plant material. A specific enzymatic method for the determination of γ-ABA acid has been known for several years. For the analysis of smaller tissue samples, however, the high sensitivity of fluorimetric measurements is required. This chapter discusses this enzymatic method. The method is applied in quantitative histo-chemical analysis and with small identifiable tissue samples, such as parts of the spinal cord of mammals, layers of the retina of amphibians, layers of the cerebellum of mammals, isolated nerve fibres, and individual cells of crustaceans. The coefficient of variation for the method is smaller than 4 %. The only other compound known to give an 2-oxoglutarate-dependent production of NADPH in the enzyme system used in this method is β-hydroxy-γ-ABA. β-hydroxy-γ-ABA reacts considerably more slowly than γ-ABA. In addition, β-hydroxy-γ-ABA does not normally occur in nervous tissue." @default.
- W2238685771 created "2016-06-24" @default.
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- W2238685771 date "1974-01-01" @default.
- W2238685771 modified "2023-09-24" @default.
- W2238685771 title "γ-Aminobutyric Acid" @default.
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- W2238685771 doi "https://doi.org/10.1016/b978-0-12-091304-6.50014-8" @default.
- W2238685771 hasPublicationYear "1974" @default.
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