Matches in SemOpenAlex for { <https://semopenalex.org/work/W2238892738> ?p ?o ?g. }
- W2238892738 endingPage "1818" @default.
- W2238892738 startingPage "1801" @default.
- W2238892738 abstract "Acinetobacter baumannii has emerged as an important opportunistic pathogen equipped with a growing number of antibiotic resistance genes. Our study investigated the molecular epidemiology and antibiotic resistance features of 28 consecutive carbapenem-resistant clinical isolates of A. baumannii collected throughout Sweden in 2012 and 2013. The isolates mainly belonged to clonal complexes (CCs) with an extensive international distribution, such as CC2 (n = 16) and CC25 (n = 7). Resistance to carbapenems was related to blaOXA-23 (20 isolates), blaOXA-24/40-like (6 isolates), blaOXA-467 (1 isolate), and ISAba1-blaOXA-69 (1 isolate). Ceftazidime resistance was associated with blaPER-7 in the CC25 isolates. Two classical point mutations were responsible for resistance to quinolones in all the isolates. Isolates with high levels of resistance to aminoglycosides carried the 16S rRNA methylase armA gene. The isolates also carried a variety of genes encoding aminoglycoside-modifying enzymes. Several novel structures involved in aminoglycoside resistance were identified, including Tn6279, ΔTn6279, Ab-ST3-aadB, and different assemblies of Tn6020 and TnaphA6. Importantly, a number of circular forms related to the IS26 or ISAba125 composite transposons were detected. The frequent occurrence of these circular forms in the populations of several isolates indicates a potential role of these circular forms in the dissemination of antibiotic resistance genes." @default.
- W2238892738 created "2016-06-24" @default.
- W2238892738 creator A5022926262 @default.
- W2238892738 creator A5033301409 @default.
- W2238892738 creator A5044456520 @default.
- W2238892738 creator A5053096276 @default.
- W2238892738 creator A5059396317 @default.
- W2238892738 creator A5063587926 @default.
- W2238892738 creator A5083598514 @default.
- W2238892738 date "2016-03-01" @default.
- W2238892738 modified "2023-10-14" @default.
- W2238892738 title "Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates" @default.
- W2238892738 cites W1930734356 @default.
- W2238892738 cites W1955612312 @default.
- W2238892738 cites W1966822396 @default.
- W2238892738 cites W1971676416 @default.
- W2238892738 cites W1985172464 @default.
- W2238892738 cites W1989648531 @default.
- W2238892738 cites W2001696260 @default.
- W2238892738 cites W2006881751 @default.
- W2238892738 cites W2007016630 @default.
- W2238892738 cites W2009291413 @default.
- W2238892738 cites W2018704865 @default.
- W2238892738 cites W2023087318 @default.
- W2238892738 cites W2024919881 @default.
- W2238892738 cites W2024947920 @default.
- W2238892738 cites W2024986596 @default.
- W2238892738 cites W2030323881 @default.
- W2238892738 cites W2032507066 @default.
- W2238892738 cites W2040642086 @default.
- W2238892738 cites W2041340029 @default.
- W2238892738 cites W2048103253 @default.
- W2238892738 cites W2062320429 @default.
- W2238892738 cites W2067470076 @default.
- W2238892738 cites W2069200382 @default.
- W2238892738 cites W2071982043 @default.
- W2238892738 cites W2072172816 @default.
- W2238892738 cites W2074663598 @default.
- W2238892738 cites W2083022967 @default.
- W2238892738 cites W2091957867 @default.
- W2238892738 cites W2101610299 @default.
- W2238892738 cites W2103243920 @default.
- W2238892738 cites W2105393577 @default.
- W2238892738 cites W2106574670 @default.
- W2238892738 cites W2109142716 @default.
- W2238892738 cites W2111819265 @default.
- W2238892738 cites W2112589522 @default.
- W2238892738 cites W2112676175 @default.
- W2238892738 cites W2113561237 @default.
- W2238892738 cites W2115118328 @default.
- W2238892738 cites W2115704819 @default.
- W2238892738 cites W2116465275 @default.
- W2238892738 cites W2117043113 @default.
- W2238892738 cites W2121361439 @default.
- W2238892738 cites W2121822413 @default.
- W2238892738 cites W2121998313 @default.
- W2238892738 cites W2124401047 @default.
- W2238892738 cites W2127653962 @default.
- W2238892738 cites W2133504563 @default.
- W2238892738 cites W2134852597 @default.
- W2238892738 cites W2135396450 @default.
- W2238892738 cites W2137108244 @default.
- W2238892738 cites W2139363194 @default.
- W2238892738 cites W2139580695 @default.
- W2238892738 cites W2142095293 @default.
- W2238892738 cites W2144270650 @default.
- W2238892738 cites W2146049144 @default.
- W2238892738 cites W2149452073 @default.
- W2238892738 cites W2149835325 @default.
- W2238892738 cites W2159435953 @default.
- W2238892738 cites W2160161568 @default.
- W2238892738 cites W2163494064 @default.
- W2238892738 cites W2169499475 @default.
- W2238892738 cites W2170246082 @default.
- W2238892738 cites W2171348592 @default.
- W2238892738 doi "https://doi.org/10.1128/aac.02143-15" @default.
- W2238892738 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4776018" @default.
- W2238892738 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26824943" @default.
- W2238892738 hasPublicationYear "2016" @default.
- W2238892738 type Work @default.
- W2238892738 sameAs 2238892738 @default.
- W2238892738 citedByCount "49" @default.
- W2238892738 countsByYear W22388927382016 @default.
- W2238892738 countsByYear W22388927382017 @default.
- W2238892738 countsByYear W22388927382018 @default.
- W2238892738 countsByYear W22388927382019 @default.
- W2238892738 countsByYear W22388927382020 @default.
- W2238892738 countsByYear W22388927382021 @default.
- W2238892738 countsByYear W22388927382022 @default.
- W2238892738 countsByYear W22388927382023 @default.
- W2238892738 crossrefType "journal-article" @default.
- W2238892738 hasAuthorship W2238892738A5022926262 @default.
- W2238892738 hasAuthorship W2238892738A5033301409 @default.
- W2238892738 hasAuthorship W2238892738A5044456520 @default.
- W2238892738 hasAuthorship W2238892738A5053096276 @default.
- W2238892738 hasAuthorship W2238892738A5059396317 @default.
- W2238892738 hasAuthorship W2238892738A5063587926 @default.
- W2238892738 hasAuthorship W2238892738A5083598514 @default.