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- W2238972497 abstract "Working memory deficits, a core cognitive feature of schizophrenia may arise from dysfunction in the frontal and parietal cortices. Numerous studies have also found abnormal neural activation during working memory tasks in patients' unaffected relatives. The aim of this study was to systematically identify and anatomically localize the evidence for those activation differences across all eligible studies. Fifteen functional magnetic resonance imaging (fMRI) manuscripts, containing 16 samples of 289 unaffected relatives of patients with schizophrenia, and 358 healthy controls were identified that met our inclusion criteria: (1) used a working memory task; and (2) reported standard space coordinates. Activation likelihood estimation (ALE) identified convergence across studies. Compared to healthy controls, patients' unaffected relatives showed decreases in neural activation in the right middle frontal gyrus (BA9), as well as right inferior frontal gyrus (BA44). Increased activation was seen in relatives in the right frontopolar (BA10), left inferior parietal lobe (BA40), and thalamus bilaterally. These results suggest that the familial risk of schizophrenia is expressed in changes in neural activation in the unaffected relatives in the cortical-subcortical working memory network that includes, but is not restricted to the middle prefrontal cortex." @default.
- W2238972497 created "2016-06-24" @default.
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- W2238972497 creator A5006956399 @default.
- W2238972497 creator A5053278692 @default.
- W2238972497 creator A5083805114 @default.
- W2238972497 date "2016-01-05" @default.
- W2238972497 modified "2023-10-01" @default.
- W2238972497 title "Working Memory in Unaffected Relatives of Patients With Schizophrenia: A Meta-Analysis of Functional Magnetic Resonance Imaging Studies" @default.
- W2238972497 cites W1524835549 @default.
- W2238972497 cites W1633838156 @default.
- W2238972497 cites W1936789326 @default.
- W2238972497 cites W1965146482 @default.
- W2238972497 cites W1977717531 @default.
- W2238972497 cites W1979423827 @default.
- W2238972497 cites W1980484367 @default.
- W2238972497 cites W1983695475 @default.
- W2238972497 cites W1994903712 @default.
- W2238972497 cites W2000697043 @default.
- W2238972497 cites W2007545129 @default.
- W2238972497 cites W2007610410 @default.
- W2238972497 cites W2008919084 @default.
- W2238972497 cites W2017806432 @default.
- W2238972497 cites W2020575476 @default.
- W2238972497 cites W2022843626 @default.
- W2238972497 cites W2025635418 @default.
- W2238972497 cites W2028400383 @default.
- W2238972497 cites W2030645204 @default.
- W2238972497 cites W2036597812 @default.
- W2238972497 cites W2039744775 @default.
- W2238972497 cites W2049335636 @default.
- W2238972497 cites W2052124027 @default.
- W2238972497 cites W2056759470 @default.
- W2238972497 cites W2060259401 @default.
- W2238972497 cites W2060885915 @default.
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- W2238972497 cites W2066785847 @default.
- W2238972497 cites W2067209719 @default.
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- W2238972497 cites W2074117397 @default.
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- W2238972497 cites W2090084259 @default.
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- W2238972497 cites W2095945552 @default.
- W2238972497 cites W2101357408 @default.
- W2238972497 cites W2103655132 @default.
- W2238972497 cites W2107544270 @default.
- W2238972497 cites W2108599940 @default.
- W2238972497 cites W2115687188 @default.
- W2238972497 cites W2120515742 @default.
- W2238972497 cites W2120839417 @default.
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- W2238972497 cites W2123232640 @default.
- W2238972497 cites W2126407771 @default.
- W2238972497 cites W2132168166 @default.
- W2238972497 cites W2134610285 @default.
- W2238972497 cites W2134676768 @default.
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- W2238972497 cites W2139977289 @default.
- W2238972497 cites W2142837020 @default.
- W2238972497 cites W2145178659 @default.
- W2238972497 cites W2146738944 @default.
- W2238972497 cites W2148940212 @default.
- W2238972497 cites W2149849282 @default.
- W2238972497 cites W2152284414 @default.
- W2238972497 cites W2155846146 @default.
- W2238972497 cites W2160022744 @default.
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- W2238972497 cites W2162931666 @default.
- W2238972497 cites W2162950935 @default.
- W2238972497 cites W2163147213 @default.
- W2238972497 cites W2164025570 @default.
- W2238972497 cites W2166025578 @default.
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- W2238972497 cites W2172120139 @default.
- W2238972497 cites W2315267894 @default.
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- W2238972497 doi "https://doi.org/10.1093/schbul/sbv221" @default.
- W2238972497 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4903055" @default.
- W2238972497 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26738528" @default.
- W2238972497 hasPublicationYear "2016" @default.
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