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- W2239174029 abstract "This chapter discusses clinical laboratory serum hCG tests and point-of-care (POC) and over-the-counter (OTC) pregnancy tests. All these tests seem so well designed and might appear to be perfect; however, when dealing with the specificities of these tests, it becomes apparent that they are not perfect. Hyperglycosylated hCG (hCG-H) is the principal hCG form present during the first weeks of pregnancy testing. Two clinical laboratory serum hCG tests do not appear to be suitable for early pregnancy testing because they poorly detected hCG-H. The bulk of clinical laboratory tests, in contrast, do not detect the degradation product hCG missing the β-subunit C-terminal peptide (βCTP), which makes them unsuitable for monitoring cancer and gestational trophoblastic disease patients. Radical statements need to be me made by manufacturers that assays are not suitable for early pregnancy and not appropriate for monitoring cancer and gestational trophoblastic disease. This chapter analyzes the suitability of different blood and urine hCG tests for pregnancy detection and for monitoring cancer and gestational trophoblastic disease cases." @default.
- W2239174029 created "2016-06-24" @default.
- W2239174029 creator A5059355586 @default.
- W2239174029 date "2010-01-01" @default.
- W2239174029 modified "2023-09-23" @default.
- W2239174029 title "Specificity of Different hCG Assays" @default.
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- W2239174029 doi "https://doi.org/10.1016/b978-0-12-384907-6.00021-9" @default.
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