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- W2240056421 abstract "We have observed that in the absence of hydrogen peroxide the Fe(III)-bleomycin (BLM) complex exhibits high DNA cleavage efficiency, converting supercoiled Form I DNA (pBR322 or phix174) to Form II (nicked, relaxed circular); the present study may give an important clue to elucidate the fact that iron-bleomycin mediated double-strand DNA cleavage requires at least one molecule of oxygen (O2) over the amount required to form 'activated bleomycin." @default.
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- W2240056421 date "1998-10-01" @default.
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- W2240056421 title "Mechanism of Double-Strand DNA Cleavage Effected by Iron-Bleomycin" @default.
- W2240056421 doi "https://doi.org/10.1515/znc-1998-9-1014" @default.
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