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• W2240213174 abstract "<h3>Objective</h3> To compare patching and atropine sulfate as treatments for moderate amblyopia in children 18 months after completion of a 6-month randomized trial. <h3>Methods</h3> In a randomized, multicenter (47 sites) clinical trial, 419 children younger than 7 years with amblyopia (20/40 to 20/100 in the affected eye) were assigned to receive either patching or atropine eye drops for 6 months. Between 6 months and 2 years, treatment was at the discretion of the investigator. <h3>Main Outcome Measure</h3> Visual acuity in the amblyopic eye and sound eye after 2 years. <h3>Results</h3> At 2 years, visual acuity in the amblyopic eye improved from baseline a mean of 3.7 lines in the patching group and 3.6 lines in the atropine group. The difference in visual acuity between treatment groups was small: 0.01 logMAR (95% confidence interval, −0.02 to 0.04). In both treatment groups, the mean amblyopic eye acuity was approximately 20/32, 1.8 lines worse than the mean sound eye acuity, which was approximately 20/20. <h3>Conclusions</h3> Atropine or patching for 6 months followed by best clinical care until 2 years produced similar improvement of moderate amblyopia in children between 3 and 7 years of age at enrollment. However, on average the amblyopic eye acuity was still approximately 2 lines worse than the sound eye." @default.
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• W2240213174 date "2005-02-01" @default.
• W2240213174 modified "2023-10-16" @default.
• W2240213174 title "Two-Year Follow-up of a 6-Month Randomized Trial of Atropine vs Patching for Treatment of Moderate Amblyopia in Children" @default.
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• W2240213174 doi "https://doi.org/10.1001/archopht.123.2.149" @default.
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