Matches in SemOpenAlex for { <https://semopenalex.org/work/W2240379211> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2240379211 endingPage "237" @default.
- W2240379211 startingPage "232" @default.
- W2240379211 abstract "Background and Objectives : Cholera toxin B (CTB) is an effective immunomodulating agent. Mucosal tolerance is a wellrecognized method for inducing tolerance, but large amounts of antigen is needed. The dosage required can be dramatically reduced through coupling the antigen to the CTB. This study aimed to examine whether mucosal administration of house dust mitecoupled to CTB (HDM-CTB conjugate) would modulate specific type 1 hypersensitivity in the murine model of allergic rhinitisand to evaluate the prophylactic and long-term therapeutic effects. Materials and Method : C57BL/6 mice were sensitized withDermatophagoides farinae extract. After administration of HDM-CTB conjugate, several parameters of alleigic response were evaluated. Results : After mucosal adminstration of HDM-CTB conjugate, allergic symptoms, eosinophilic infiltration into nasal mucosa,spedfic IgE, and the splenic T cell proliferation after Dermatophagoides farinae alleigen challenge were suppressed, ConclusionThese findings show that HDM-CTB conjugate has an anti-allergic effect in the murine model of alleigic rhinitis and suggest thathouse dust mite allergy can be modulated with mucosal administration of allergen coupled to CTB." @default.
- W2240379211 created "2016-06-24" @default.
- W2240379211 creator A5002446662 @default.
- W2240379211 creator A5013714253 @default.
- W2240379211 creator A5014390131 @default.
- W2240379211 creator A5046198396 @default.
- W2240379211 creator A5050118062 @default.
- W2240379211 creator A5052078652 @default.
- W2240379211 creator A5073588318 @default.
- W2240379211 creator A5078793398 @default.
- W2240379211 creator A5083229449 @default.
- W2240379211 date "2004-03-01" @default.
- W2240379211 modified "2023-10-18" @default.
- W2240379211 title "Induction of Mucosal Tolerance Using House Dust Mite-Cholera Toxin B Conjugate in Mouse Model of Allergic Rhinitis: Prophylactic and Long-Term Therapeutic Effects" @default.
- W2240379211 hasPublicationYear "2004" @default.
- W2240379211 type Work @default.
- W2240379211 sameAs 2240379211 @default.
- W2240379211 citedByCount "0" @default.
- W2240379211 crossrefType "journal-article" @default.
- W2240379211 hasAuthorship W2240379211A5002446662 @default.
- W2240379211 hasAuthorship W2240379211A5013714253 @default.
- W2240379211 hasAuthorship W2240379211A5014390131 @default.
- W2240379211 hasAuthorship W2240379211A5046198396 @default.
- W2240379211 hasAuthorship W2240379211A5050118062 @default.
- W2240379211 hasAuthorship W2240379211A5052078652 @default.
- W2240379211 hasAuthorship W2240379211A5073588318 @default.
- W2240379211 hasAuthorship W2240379211A5078793398 @default.
- W2240379211 hasAuthorship W2240379211A5083229449 @default.
- W2240379211 hasConcept C126322002 @default.
- W2240379211 hasConcept C134306372 @default.
- W2240379211 hasConcept C141105273 @default.
- W2240379211 hasConcept C147483822 @default.
- W2240379211 hasConcept C159654299 @default.
- W2240379211 hasConcept C170493617 @default.
- W2240379211 hasConcept C197336794 @default.
- W2240379211 hasConcept C203014093 @default.
- W2240379211 hasConcept C207480886 @default.
- W2240379211 hasConcept C2776953665 @default.
- W2240379211 hasConcept C2777006276 @default.
- W2240379211 hasConcept C2777702733 @default.
- W2240379211 hasConcept C2778166374 @default.
- W2240379211 hasConcept C2779779143 @default.
- W2240379211 hasConcept C2780510475 @default.
- W2240379211 hasConcept C33923547 @default.
- W2240379211 hasConcept C71924100 @default.
- W2240379211 hasConcept C85663871 @default.
- W2240379211 hasConceptScore W2240379211C126322002 @default.
- W2240379211 hasConceptScore W2240379211C134306372 @default.
- W2240379211 hasConceptScore W2240379211C141105273 @default.
- W2240379211 hasConceptScore W2240379211C147483822 @default.
- W2240379211 hasConceptScore W2240379211C159654299 @default.
- W2240379211 hasConceptScore W2240379211C170493617 @default.
- W2240379211 hasConceptScore W2240379211C197336794 @default.
- W2240379211 hasConceptScore W2240379211C203014093 @default.
- W2240379211 hasConceptScore W2240379211C207480886 @default.
- W2240379211 hasConceptScore W2240379211C2776953665 @default.
- W2240379211 hasConceptScore W2240379211C2777006276 @default.
- W2240379211 hasConceptScore W2240379211C2777702733 @default.
- W2240379211 hasConceptScore W2240379211C2778166374 @default.
- W2240379211 hasConceptScore W2240379211C2779779143 @default.
- W2240379211 hasConceptScore W2240379211C2780510475 @default.
- W2240379211 hasConceptScore W2240379211C33923547 @default.
- W2240379211 hasConceptScore W2240379211C71924100 @default.
- W2240379211 hasConceptScore W2240379211C85663871 @default.
- W2240379211 hasIssue "3" @default.
- W2240379211 hasLocation W22403792111 @default.
- W2240379211 hasOpenAccess W2240379211 @default.
- W2240379211 hasPrimaryLocation W22403792111 @default.
- W2240379211 hasRelatedWork W1901090519 @default.
- W2240379211 hasRelatedWork W2004399501 @default.
- W2240379211 hasRelatedWork W2022103554 @default.
- W2240379211 hasRelatedWork W2030173995 @default.
- W2240379211 hasRelatedWork W2038256962 @default.
- W2240379211 hasRelatedWork W2056660336 @default.
- W2240379211 hasRelatedWork W2066352783 @default.
- W2240379211 hasRelatedWork W2071713515 @default.
- W2240379211 hasRelatedWork W2104621944 @default.
- W2240379211 hasRelatedWork W2110727393 @default.
- W2240379211 hasRelatedWork W2295174991 @default.
- W2240379211 hasRelatedWork W2374060764 @default.
- W2240379211 hasRelatedWork W2465752583 @default.
- W2240379211 hasRelatedWork W2769472433 @default.
- W2240379211 hasRelatedWork W2783381856 @default.
- W2240379211 hasRelatedWork W2796641200 @default.
- W2240379211 hasRelatedWork W2969863396 @default.
- W2240379211 hasRelatedWork W3033717649 @default.
- W2240379211 hasRelatedWork W3144242372 @default.
- W2240379211 hasRelatedWork W3186322973 @default.
- W2240379211 hasVolume "47" @default.
- W2240379211 isParatext "false" @default.
- W2240379211 isRetracted "false" @default.
- W2240379211 magId "2240379211" @default.
- W2240379211 workType "article" @default.