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- W2240775737 abstract "Carbon nanotubes (CNTs) were reported to cause severe toxicity in in vivo and in vitro studies. On the other hand, CNTs has the potential as a mechanism for drug delivery across the blood brain barrier due to its nano-sized dimensions. The present preliminary study examined the cytotoxic effect of CNTs in serum-free and serum-containing EMEM medium on neuroblastoma cells growth. The MTS assay showed that CNTs did not cause any cytotoxicity at concentrations below 0.1 mg/mL at 24 and 48 h incubation in serum-containing EMEM medium. This finding suggested that below 0.1 mg/mL, CNTs can be used as a mechanism for drug delivery for the treatment of neuronal cancer. However, CNTs showed slighty toxic towards neuroblastoma cells at concentration 0.1 mg/ml at 48h incubation in serum-free EMEM medium. This finding indicates that the present of serum play a role for toxicity effect of CNTs in cells." @default.
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- W2240775737 date "2013-03-01" @default.
- W2240775737 modified "2023-09-24" @default.
- W2240775737 title "Carbon Nanotubes in Cancer Treatment: A Preliminary <i>In Vitro</i> Study Using Neuroblastoma Cells" @default.
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- W2240775737 doi "https://doi.org/10.4028/www.scientific.net/amr.667.155" @default.
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