Matches in SemOpenAlex for { <https://semopenalex.org/work/W2241042057> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2241042057 endingPage "10578" @default.
- W2241042057 startingPage "10578" @default.
- W2241042057 abstract "10578 Background: The best adjuvant treatment for soft tissue sarcomas is still unclear. Soft tissue sarcomas is an eterogenous group of several different hystotypes. The aim of this retrospective study is to evaluate prognostic factors and treatments. Methods: All liposarcoma cases evaluated in our Pathology from Jan 1985 to December 2005 were reviewed: 299 cases of liposarcoma were found of these only 155 were treated at Rizzoli since their first diagnosis. Metastatic since diagnosis and pediatric cases were excluded. Of these 155 pts only 122 had localized liposarcoma of soft tissue and adequate informations and follow up. Results: Male were 71 and female 51, Median age 47 (15–85). Histology was as follows: mixoid 62, round cell 33, pleomorphic 27. Grading according to FNCCL was G1=18, G2=51, G3=53. Median tumor volume was 183 cm3 (8–3,800), mean 401. Surgical margins were adequate in 84 patients (66.4%) unadequate in 34 (27.9%), 4 missing. Treatment received were: 18 no treatment besides surgery, presurgery radiotherapy (PRE-RT) alone in 52 pts, postsurgery RT (POST- RT) alone in 30 pts, chemotherapy ± RT in 22 patients. Chemotherapy was based on anthracyclin and ifosfamide scheme (3–5 cycles), RT was ranging from 4,000–4,500 cGy. Five years DFS was 50 months for all group (range 1–230) and 5 yrs OS was 64 ms (10–230). Positive prognostic factors were grading, adequate margins and mixoid histology. Then excluding 18 pts who were G1 we evaluate on the remaining 104 patients, all G 2 an 3, the 5 yrs DFS and OS according to the treatment received. 5 yr DFS was 64% for those who received no-Tx, 56.5% for those who received PRE-RT and 82% for those who received POST RT, and 55.4 for those who received chemotherapy. 5-yr OS was 80% for no-Tx group, 81% for PRE-RT, 92% for POST-RT and 79% for chemo group. OS according to histology (on 104 pts, excluding G1) was 90% for mixoid, 82.8% for round cells and 74% for pleomorphic. At multivariate analysis grading and therapy (RT POST) maintain positive significance. Conclusions: From this retrospective study POST -RT seems to be the best treatment for localized liposarcoma. No significant financial relationships to disclose." @default.
- W2241042057 created "2016-06-24" @default.
- W2241042057 creator A5000743412 @default.
- W2241042057 creator A5030668768 @default.
- W2241042057 creator A5032638492 @default.
- W2241042057 creator A5039992870 @default.
- W2241042057 creator A5047205597 @default.
- W2241042057 creator A5060586731 @default.
- W2241042057 creator A5068651198 @default.
- W2241042057 creator A5076764794 @default.
- W2241042057 creator A5080548972 @default.
- W2241042057 creator A5085277690 @default.
- W2241042057 date "2008-05-20" @default.
- W2241042057 modified "2023-09-27" @default.
- W2241042057 title "Liposarcoma treatment: Role of radiotherapy and chemotherapy" @default.
- W2241042057 doi "https://doi.org/10.1200/jco.2008.26.15_suppl.10578" @default.
- W2241042057 hasPublicationYear "2008" @default.
- W2241042057 type Work @default.
- W2241042057 sameAs 2241042057 @default.
- W2241042057 citedByCount "2" @default.
- W2241042057 countsByYear W22410420572017 @default.
- W2241042057 crossrefType "journal-article" @default.
- W2241042057 hasAuthorship W2241042057A5000743412 @default.
- W2241042057 hasAuthorship W2241042057A5030668768 @default.
- W2241042057 hasAuthorship W2241042057A5032638492 @default.
- W2241042057 hasAuthorship W2241042057A5039992870 @default.
- W2241042057 hasAuthorship W2241042057A5047205597 @default.
- W2241042057 hasAuthorship W2241042057A5060586731 @default.
- W2241042057 hasAuthorship W2241042057A5068651198 @default.
- W2241042057 hasAuthorship W2241042057A5076764794 @default.
- W2241042057 hasAuthorship W2241042057A5080548972 @default.
- W2241042057 hasAuthorship W2241042057A5085277690 @default.
- W2241042057 hasConcept C126322002 @default.
- W2241042057 hasConcept C127413603 @default.
- W2241042057 hasConcept C136948725 @default.
- W2241042057 hasConcept C141071460 @default.
- W2241042057 hasConcept C142724271 @default.
- W2241042057 hasConcept C147176958 @default.
- W2241042057 hasConcept C2776694085 @default.
- W2241042057 hasConcept C2777286243 @default.
- W2241042057 hasConcept C2777506904 @default.
- W2241042057 hasConcept C2778239845 @default.
- W2241042057 hasConcept C2778256501 @default.
- W2241042057 hasConcept C2778629024 @default.
- W2241042057 hasConcept C2779568860 @default.
- W2241042057 hasConcept C509974204 @default.
- W2241042057 hasConcept C57742111 @default.
- W2241042057 hasConcept C71924100 @default.
- W2241042057 hasConceptScore W2241042057C126322002 @default.
- W2241042057 hasConceptScore W2241042057C127413603 @default.
- W2241042057 hasConceptScore W2241042057C136948725 @default.
- W2241042057 hasConceptScore W2241042057C141071460 @default.
- W2241042057 hasConceptScore W2241042057C142724271 @default.
- W2241042057 hasConceptScore W2241042057C147176958 @default.
- W2241042057 hasConceptScore W2241042057C2776694085 @default.
- W2241042057 hasConceptScore W2241042057C2777286243 @default.
- W2241042057 hasConceptScore W2241042057C2777506904 @default.
- W2241042057 hasConceptScore W2241042057C2778239845 @default.
- W2241042057 hasConceptScore W2241042057C2778256501 @default.
- W2241042057 hasConceptScore W2241042057C2778629024 @default.
- W2241042057 hasConceptScore W2241042057C2779568860 @default.
- W2241042057 hasConceptScore W2241042057C509974204 @default.
- W2241042057 hasConceptScore W2241042057C57742111 @default.
- W2241042057 hasConceptScore W2241042057C71924100 @default.
- W2241042057 hasIssue "15_suppl" @default.
- W2241042057 hasLocation W22410420571 @default.
- W2241042057 hasOpenAccess W2241042057 @default.
- W2241042057 hasPrimaryLocation W22410420571 @default.
- W2241042057 hasRelatedWork W154651119 @default.
- W2241042057 hasRelatedWork W1978776472 @default.
- W2241042057 hasRelatedWork W2020896825 @default.
- W2241042057 hasRelatedWork W2048017835 @default.
- W2241042057 hasRelatedWork W2060449708 @default.
- W2241042057 hasRelatedWork W2134611432 @default.
- W2241042057 hasRelatedWork W2402032689 @default.
- W2241042057 hasRelatedWork W2418708708 @default.
- W2241042057 hasRelatedWork W2428197177 @default.
- W2241042057 hasRelatedWork W3169567730 @default.
- W2241042057 hasVolume "26" @default.
- W2241042057 isParatext "false" @default.
- W2241042057 isRetracted "false" @default.
- W2241042057 magId "2241042057" @default.
- W2241042057 workType "article" @default.