FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2242742846> ?p ?o ?g. }

• W2242742846 abstract "[Objective] To investigate the effects of silicon dioxide nanoparticles(nano-SiO2) of different particle size(15,30,100 nm) and standard SiO2 particles(micro-SiO2) on proliferation and apoptosis of HaCaT cells.[Method] HaCaT cells were treated by 15,30,100 nm nano-SiO2(2.5,5,10 μg/ml) particles and micro-SiO2(10 μg/ml) particles for 24 h,at the same time,the solvent control was set.The level of ROS and the effect of cell growth inhibition were assayed by 2′,7′-dichlorfluorescein-diacetate(DCFH-DA) and cell counting kit(CCK-8) Kit respectively.Apoptosis were assayed by Annexinⅴ-PI double staining and Hoechst 33342 staining method.[Method] HaCaT cells were treated by 15,30,100 nm nano-SiO2(2.5,5,10 μg/ml) particles and micro-SiO2(10 μg/ml) particles for 24 h,at the same time,the solvent control was set.The level of ROS and the effect of cell growth inhibition were assayed by 2′,7′-dichlorfluorescein-diacetate(DCFH-DA) and cell counting kit(CCK-8) Kit respectively.Apoptosis were assayed by Annexinⅴ-PI double staining and Hoechest 33342 staining method.[Result] As observed in the CCK-8 kit,exposure to nano-SiO2 nanoparticles for 24 h,the IC50 was 19.4 ± 1.3,27.7 ± 1.5 and 35.9±1.6 μg/ml for 15,30 and 100 nm SiO2 nanoparticles,respectively.Exposure to SiO2 nanoparticles results in a concentration-and size-dependent cytotoxicity and increase in intracellular ROS level and apoptosis rate were also observed in SiO2 nanoparticle-exposed HaCaT cells.Cytotoxicity and apoptosis in cultural HaCaT cells that is closely correlated to increased oxidative stress,the correlation coefficient was-0.952 and 0.898 respectively.[Conclusion] nano-SiO2 may affect proliferation and apoptotic rates of HaCaT cells via stimulating the production of ROS in cells." @default.
• W2242742846 created "2016-06-24" @default.
• W2242742846 creator A5021335041 @default.
• W2242742846 creator A5032137944 @default.
• W2242742846 creator A5053102687 @default.
• W2242742846 creator A5066867449 @default.
• W2242742846 creator A5067130875 @default.
• W2242742846 creator A5073453429 @default.
• W2242742846 creator A5076410258 @default.
• W2242742846 creator A5084444490 @default.
• W2242742846 date "2013-01-01" @default.
• W2242742846 modified "2023-09-26" @default.
• W2242742846 title "Effects of Silicon Dioxide Nanoparticles on Apoptosis of HaCaT Cells" @default.
• W2242742846 hasPublicationYear "2013" @default.
• W2242742846 type Work @default.
• W2242742846 sameAs 2242742846 @default.
• W2242742846 citedByCount "0" @default.
• W2242742846 crossrefType "journal-article" @default.
• W2242742846 hasAuthorship W2242742846A5021335041 @default.
• W2242742846 hasAuthorship W2242742846A5032137944 @default.
• W2242742846 hasAuthorship W2242742846A5053102687 @default.
• W2242742846 hasAuthorship W2242742846A5066867449 @default.
• W2242742846 hasAuthorship W2242742846A5067130875 @default.
• W2242742846 hasAuthorship W2242742846A5073453429 @default.
• W2242742846 hasAuthorship W2242742846A5076410258 @default.
• W2242742846 hasAuthorship W2242742846A5084444490 @default.
• W2242742846 hasConcept C109316439 @default.
• W2242742846 hasConcept C118995209 @default.
• W2242742846 hasConcept C12554922 @default.
• W2242742846 hasConcept C13965031 @default.
• W2242742846 hasConcept C147789679 @default.
• W2242742846 hasConcept C153911025 @default.
• W2242742846 hasConcept C155672457 @default.
• W2242742846 hasConcept C171250308 @default.
• W2242742846 hasConcept C185592680 @default.
• W2242742846 hasConcept C187530423 @default.
• W2242742846 hasConcept C190283241 @default.
• W2242742846 hasConcept C191897082 @default.
• W2242742846 hasConcept C192562407 @default.
• W2242742846 hasConcept C202751555 @default.
• W2242742846 hasConcept C2583947 @default.
• W2242742846 hasConcept C2779089622 @default.
• W2242742846 hasConcept C29537977 @default.
• W2242742846 hasConcept C53009064 @default.
• W2242742846 hasConcept C54355233 @default.
• W2242742846 hasConcept C55493867 @default.
• W2242742846 hasConcept C62112901 @default.
• W2242742846 hasConcept C74864618 @default.
• W2242742846 hasConcept C79879829 @default.
• W2242742846 hasConcept C86803240 @default.
• W2242742846 hasConcept C88634738 @default.
• W2242742846 hasConceptScore W2242742846C109316439 @default.
• W2242742846 hasConceptScore W2242742846C118995209 @default.
• W2242742846 hasConceptScore W2242742846C12554922 @default.
• W2242742846 hasConceptScore W2242742846C13965031 @default.
• W2242742846 hasConceptScore W2242742846C147789679 @default.
• W2242742846 hasConceptScore W2242742846C153911025 @default.
• W2242742846 hasConceptScore W2242742846C155672457 @default.
• W2242742846 hasConceptScore W2242742846C171250308 @default.
• W2242742846 hasConceptScore W2242742846C185592680 @default.
• W2242742846 hasConceptScore W2242742846C187530423 @default.
• W2242742846 hasConceptScore W2242742846C190283241 @default.
• W2242742846 hasConceptScore W2242742846C191897082 @default.
• W2242742846 hasConceptScore W2242742846C192562407 @default.
• W2242742846 hasConceptScore W2242742846C202751555 @default.
• W2242742846 hasConceptScore W2242742846C2583947 @default.
• W2242742846 hasConceptScore W2242742846C2779089622 @default.
• W2242742846 hasConceptScore W2242742846C29537977 @default.
• W2242742846 hasConceptScore W2242742846C53009064 @default.
• W2242742846 hasConceptScore W2242742846C54355233 @default.
• W2242742846 hasConceptScore W2242742846C55493867 @default.
• W2242742846 hasConceptScore W2242742846C62112901 @default.
• W2242742846 hasConceptScore W2242742846C74864618 @default.
• W2242742846 hasConceptScore W2242742846C79879829 @default.
• W2242742846 hasConceptScore W2242742846C86803240 @default.
• W2242742846 hasConceptScore W2242742846C88634738 @default.
• W2242742846 hasIssue "11" @default.
• W2242742846 hasLocation W22427428461 @default.
• W2242742846 hasOpenAccess W2242742846 @default.
• W2242742846 hasPrimaryLocation W22427428461 @default.
• W2242742846 hasRelatedWork W2068876948 @default.
• W2242742846 hasRelatedWork W2101862053 @default.
• W2242742846 hasRelatedWork W2347974371 @default.
• W2242742846 hasRelatedWork W2352653855 @default.
• W2242742846 hasRelatedWork W2355990084 @default.
• W2242742846 hasRelatedWork W2359335963 @default.
• W2242742846 hasRelatedWork W2363547100 @default.
• W2242742846 hasRelatedWork W2366346995 @default.
• W2242742846 hasRelatedWork W2367285186 @default.
• W2242742846 hasRelatedWork W2377187940 @default.
• W2242742846 hasRelatedWork W2379338803 @default.
• W2242742846 hasRelatedWork W2385428541 @default.
• W2242742846 hasRelatedWork W2385692343 @default.
• W2242742846 hasRelatedWork W2386322858 @default.
• W2242742846 hasRelatedWork W2389596193 @default.
• W2242742846 hasRelatedWork W2390454570 @default.
• W2242742846 hasRelatedWork W2509545452 @default.
• W2242742846 hasRelatedWork W3010076284 @default.
• W2242742846 hasRelatedWork W3029275469 @default.
• W2242742846 hasRelatedWork W3031636174 @default.

• next