FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2243202020> ?p ?o ?g. }

• W2243202020 abstract "In order to reconstruct the underlying active neural sources of epileptic spiking activity measured with scalp- EEG, it is necessary to construct a volume conductor model (VCM) reflecting the geometrical and electromagnetic properties of the head. Often three-shell spherical VCMs are used [1]. Based on boundary element methods (BEM) the patient’s anatomy can be approximated better. In these models, the head is modelled as a 3-layered VCM including scalp, skull and brain tissue [2]. The most realistic models can be constructed using finite element or finite difference techniques (FDM) [3]. Using these techniques many extra tissue types can be incorporated such as CSF, grey and white matter based on MRI tissue segmentation techniques. In this study we investigated the effect of the VCM on spike localization. We used a FDM forward solver to compare three types of models: (i) three-layered spherical models, (ii) three-layered BEM-like models, (iii) 5-layered models using SPM segmentation and (iv) 5-layered models using a segmentation method based on level-set (LS) [4]. For each of the models we assumed the same conductivity for equivalent tissue classes and constrained the solution space to the grey matter subspace segmented from the MR [4]. We used a single dipole model to reconstruct 27-channel EEG spiking activity in 4 patients that underwent epilepsy surgery and have been seizure-free since then. CT-images were available to extract the electrode positions. We applied single dipole spike localization using least squares minimisation and validated the estimated sources against the resected area, as indicated by the post-operative MRI and serving as our ground truth. The closest distance of the estimated dipole to the resected area was used as a measure of localization accuracy. In all 4 patients we found the smallest distances using the most realistic 5-layered VCMs (iii) and (iv). The maximum error was 5 mm. We didn’t find significant differences between level-set and SPM segmentation. For the BEM and the spherical models, the error was bigger ranging from 5 mm to 40 mm from the resected zone. We can therefore preliminary conclude that it is worth the effort to build realistic VCMs including more tissue types, based on the MRI segmentation of the patient’s head. This is especially useful in the presurgical evaluation of patients with refractory epilepsy, where the precise determination of the ictal onset zone is very important." @default.
• W2243202020 created "2016-06-24" @default.
• W2243202020 creator A5019775520 @default.
• W2243202020 creator A5047464806 @default.
• W2243202020 creator A5048790815 @default.
• W2243202020 creator A5052625890 @default.
• W2243202020 creator A5075944478 @default.
• W2243202020 date "2013-01-01" @default.
• W2243202020 modified "2023-09-27" @default.
• W2243202020 title "Selecting volume conductor models for EEG source localization of epileptic spikes: preliminary results based on 4 operated epileptic patients" @default.
• W2243202020 hasPublicationYear "2013" @default.
• W2243202020 type Work @default.
• W2243202020 sameAs 2243202020 @default.
• W2243202020 citedByCount "1" @default.
• W2243202020 countsByYear W22432020202014 @default.
• W2243202020 crossrefType "journal-article" @default.
• W2243202020 hasAuthorship W2243202020A5019775520 @default.
• W2243202020 hasAuthorship W2243202020A5047464806 @default.
• W2243202020 hasAuthorship W2243202020A5048790815 @default.
• W2243202020 hasAuthorship W2243202020A5052625890 @default.
• W2243202020 hasAuthorship W2243202020A5075944478 @default.
• W2243202020 hasConcept C121332964 @default.
• W2243202020 hasConcept C127413603 @default.
• W2243202020 hasConcept C135628077 @default.
• W2243202020 hasConcept C136229726 @default.
• W2243202020 hasConcept C153180895 @default.
• W2243202020 hasConcept C154945302 @default.
• W2243202020 hasConcept C169760540 @default.
• W2243202020 hasConcept C199360897 @default.
• W2243202020 hasConcept C2778770139 @default.
• W2243202020 hasConcept C32834561 @default.
• W2243202020 hasConcept C41008148 @default.
• W2243202020 hasConcept C522805319 @default.
• W2243202020 hasConcept C54170458 @default.
• W2243202020 hasConcept C63632240 @default.
• W2243202020 hasConcept C86803240 @default.
• W2243202020 hasConcept C89600930 @default.
• W2243202020 hasConcept C97355855 @default.
• W2243202020 hasConceptScore W2243202020C121332964 @default.
• W2243202020 hasConceptScore W2243202020C127413603 @default.
• W2243202020 hasConceptScore W2243202020C135628077 @default.
• W2243202020 hasConceptScore W2243202020C136229726 @default.
• W2243202020 hasConceptScore W2243202020C153180895 @default.
• W2243202020 hasConceptScore W2243202020C154945302 @default.
• W2243202020 hasConceptScore W2243202020C169760540 @default.
• W2243202020 hasConceptScore W2243202020C199360897 @default.
• W2243202020 hasConceptScore W2243202020C2778770139 @default.
• W2243202020 hasConceptScore W2243202020C32834561 @default.
• W2243202020 hasConceptScore W2243202020C41008148 @default.
• W2243202020 hasConceptScore W2243202020C522805319 @default.
• W2243202020 hasConceptScore W2243202020C54170458 @default.
• W2243202020 hasConceptScore W2243202020C63632240 @default.
• W2243202020 hasConceptScore W2243202020C86803240 @default.
• W2243202020 hasConceptScore W2243202020C89600930 @default.
• W2243202020 hasConceptScore W2243202020C97355855 @default.
• W2243202020 hasLocation W22432020201 @default.
• W2243202020 hasOpenAccess W2243202020 @default.
• W2243202020 hasPrimaryLocation W22432020201 @default.
• W2243202020 hasRelatedWork W1970227782 @default.
• W2243202020 hasRelatedWork W1985975935 @default.
• W2243202020 hasRelatedWork W1988179790 @default.
• W2243202020 hasRelatedWork W1994691481 @default.
• W2243202020 hasRelatedWork W2020735372 @default.
• W2243202020 hasRelatedWork W203781398 @default.
• W2243202020 hasRelatedWork W2051866391 @default.
• W2243202020 hasRelatedWork W2079158221 @default.
• W2243202020 hasRelatedWork W2086140389 @default.
• W2243202020 hasRelatedWork W2086938063 @default.
• W2243202020 hasRelatedWork W2106294451 @default.
• W2243202020 hasRelatedWork W2111913289 @default.
• W2243202020 hasRelatedWork W2115101095 @default.
• W2243202020 hasRelatedWork W2121255253 @default.
• W2243202020 hasRelatedWork W2131193744 @default.
• W2243202020 hasRelatedWork W2144399784 @default.
• W2243202020 hasRelatedWork W2149559081 @default.
• W2243202020 hasRelatedWork W2154996297 @default.
• W2243202020 hasRelatedWork W2159965356 @default.
• W2243202020 hasRelatedWork W289951537 @default.
• W2243202020 isParatext "false" @default.
• W2243202020 isRetracted "false" @default.
• W2243202020 magId "2243202020" @default.
• W2243202020 workType "article" @default.