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- W2243322290 abstract "A convenient, one-pot, two-component synthesis of 2-(1-amidoalkyl)pyridines is reported, based upon the substitution of suitably-activated pyridine N -oxides by azlactone nucleophiles, followed by decarboxylative azlactone ring-opening. The synthesis obviates the need for precious metal catalysts to achieve a formal enolate arylation reaction, and constitutes a formally ‘umpoled’ approach to this valuable class of bioactive structures." @default.
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- W2243322290 date "2016-01-04" @default.
- W2243322290 modified "2023-09-30" @default.
- W2243322290 title "A convergent, umpoled synthesis of 2-(1-amidoalkyl)pyridines" @default.
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- W2243322290 doi "https://doi.org/10.3762/bjoc.12.1" @default.
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